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Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response.
Jena KK, Mehto S, Nath P, Chauhan NR, Sahu R, Dhar K, Das SK, Kolapalli SP, Murmu KC, Jain A, Krishna S, Sahoo BS, Chattopadhyay S, Rusten TE, Prasad P, Chauhan S, Chauhan S. Jena KK, et al. Among authors: chauhan s, chauhan nr. EMBO Rep. 2020 Sep 3;21(9):e50051. doi: 10.15252/embr.202050051. Epub 2020 Jul 27. EMBO Rep. 2020. PMID: 32715615 Free PMC article.
IRGM links autoimmunity to autophagy.
Nath P, Jena KK, Mehto S, Chauhan NR, Sahu R, Dhar K, Srinivas K, Chauhan S, Chauhan S. Nath P, et al. Among authors: chauhan s, chauhan nr. Autophagy. 2021 Feb;17(2):578-580. doi: 10.1080/15548627.2020.1810920. Epub 2020 Aug 23. Autophagy. 2021. PMID: 32813580 Free PMC article. Review.
Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses.
Nath P, Chauhan NR, Jena KK, Datey A, Kumar ND, Mehto S, De S, Nayak TK, Priyadarsini S, Rout K, Bal R, Murmu KC, Kalia M, Patnaik S, Prasad P, Reggiori F, Chattopadhyay S, Chauhan S. Nath P, et al. Among authors: chauhan s, chauhan nr. EMBO Rep. 2021 Nov 4;22(11):e52948. doi: 10.15252/embr.202152948. Epub 2021 Sep 1. EMBO Rep. 2021. PMID: 34467632 Free PMC article.
47 results