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mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein.
Chen J, Wu X, Lin J, Levine AJ. Chen J, et al. Mol Cell Biol. 1996 May;16(5):2445-52. doi: 10.1128/MCB.16.5.2445. Mol Cell Biol. 1996. PMID: 8628312 Free PMC article.
This physical interaction results in the inhibition of the transcriptional functions of p53 (J. Chen, J. Lin, and A. J. Levine, Mol. Med. 1:142-152, 1995, and J. Momand, G. P. Zambetti, D. C. Olson, D. George, and A. J. Levine, Cell 69:12 …
This physical interaction results in the inhibition of the transcriptional functions of p53 (J. Chen, J. Lin, and A. …
Temperature-sensitive mutants of p53 homologs.
Pochampally R, Li C, Lu W, Chen L, Luftig R, Lin J, Chen J. Pochampally R, et al. Among authors: chen j, chen l. Biochem Biophys Res Commun. 2000 Dec 29;279(3):1001-10. doi: 10.1006/bbrc.2000.4056. Biochem Biophys Res Commun. 2000. PMID: 11162465
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