Chen J - Search Results

1

Dimethyl fumarate alters intracellular Ca²⁺ handling in immune cells by redox-mediated pleiotropic effects.

Herrmann AK, Wüllner V, Moos S, Graf J, Chen J, Kieseier B, Kurschus FC, Albrecht P, Vangheluwe P, Methner A. Herrmann AK, et al. Among authors: chen j. Free Radic Biol Med. 2019 Sep;141:338-347. doi: 10.1016/j.freeradbiomed.2019.07.005. Epub 2019 Jul 4. Free Radic Biol Med. 2019. PMID: 31279969

2

SPCA2 couples Ca²⁺ influx via Orai1 to Ca²⁺ uptake into the Golgi/secretory pathway.

Smaardijk S, Chen J, Wuytack F, Vangheluwe P. Smaardijk S, et al. Among authors: chen j. Tissue Cell. 2017 Apr;49(2 Pt A):141-149. doi: 10.1016/j.tice.2016.09.004. Epub 2016 Sep 17. Tissue Cell. 2017. PMID: 27692665

3

Primary Active Ca²⁺ Transport Systems in Health and Disease.

Chen J, Sitsel A, Benoy V, Sepúlveda MR, Vangheluwe P. Chen J, et al. Cold Spring Harb Perspect Biol. 2020 Feb 3;12(2):a035113. doi: 10.1101/cshperspect.a035113. Cold Spring Harb Perspect Biol. 2020. PMID: 31501194 Free PMC article. Review.

4

Store-independent coupling between the Secretory Pathway Ca²⁺ transport ATPase SPCA1 and Orai1 in Golgi stress and Hailey-Hailey disease.

Smaardijk S, Chen J, Kerselaers S, Voets T, Eggermont J, Vangheluwe P. Smaardijk S, et al. Among authors: chen j. Biochim Biophys Acta Mol Cell Res. 2018 Jun;1865(6):855-862. doi: 10.1016/j.bbamcr.2018.03.007. Epub 2018 Mar 17. Biochim Biophys Acta Mol Cell Res. 2018. PMID: 29555205 Free article.

5

Contractile Behavior of Mouse Aorta Depends on SERCA2 Isoform Distribution: Effects of Replacing SERCA2a by SERCA2b.

Fransen P, Chen J, Vangheluwe P, Guns PJ. Fransen P, et al. Among authors: chen j. Front Physiol. 2020 Mar 31;11:282. doi: 10.3389/fphys.2020.00282. eCollection 2020. Front Physiol. 2020. PMID: 32296344 Free PMC article.

6

Structures of the heart specific SERCA2a Ca²⁺-ATPase.

Sitsel A, De Raeymaecker J, Drachmann ND, Derua R, Smaardijk S, Andersen JL, Vandecaetsbeek I, Chen J, De Maeyer M, Waelkens E, Olesen C, Vangheluwe P, Nissen P. Sitsel A, et al. Among authors: chen j. EMBO J. 2019 Mar 1;38(5):e100020. doi: 10.15252/embj.2018100020. Epub 2019 Feb 18. EMBO J. 2019. PMID: 30777856 Free PMC article.

7

An N-terminal Ca²⁺-binding motif regulates the secretory pathway Ca²⁺/Mn²⁺-transport ATPase SPCA1.

Chen J, Smaardijk S, Mattelaer CA, Pamula F, Vandecaetsbeek I, Vanoevelen J, Wuytack F, Lescrinier E, Eggermont J, Vangheluwe P. Chen J, et al. J Biol Chem. 2019 May 10;294(19):7878-7891. doi: 10.1074/jbc.RA118.006250. Epub 2019 Mar 28. J Biol Chem. 2019. PMID: 30923126 Free PMC article.

8

The alkalinizing, lysosomotropic agent ML-9 induces a pH-dependent depletion of ER Ca²⁺ stores in cellulo.

Kerkhofs M, Vervloessem T, Luyten T, Stopa KB, Chen J, Vangheluwe P, Bultynck G, Vervliet T. Kerkhofs M, et al. Among authors: chen j. Biochim Biophys Acta Mol Cell Res. 2022 Oct;1869(10):119308. doi: 10.1016/j.bbamcr.2022.119308. Epub 2022 Jun 13. Biochim Biophys Acta Mol Cell Res. 2022. PMID: 35710019 Free article.

9

Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca²⁺/Mn²⁺-transport ATPase (SPCA1a).

Chen J, De Raeymaecker J, Hovgaard JB, Smaardijk S, Vandecaetsbeek I, Wuytack F, Møller JV, Eggermont J, De Maeyer M, Christensen SB, Vangheluwe P. Chen J, et al. J Biol Chem. 2017 Apr 28;292(17):6938-6951. doi: 10.1074/jbc.M117.778431. Epub 2017 Mar 6. J Biol Chem. 2017. PMID: 28264934 Free PMC article.

10

Negative chronotropism, positive inotropism and lusitropism of 3,5-di-t-butyl-4-hydroxyanisole (DTBHA) on rat heart preparations occur through reduction of RyR2 Ca²⁺ leak.

Pessina F, Gamberucci A, Chen J, Liu B, Vangheluwe P, Gorelli B, Lorenzini S, Spiga O, Trezza A, Sgaragli G, Saponara S. Pessina F, et al. Among authors: chen j. Biochem Pharmacol. 2018 Sep;155:434-443. doi: 10.1016/j.bcp.2018.07.026. Epub 2018 Jul 21. Biochem Pharmacol. 2018. PMID: 30036502

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