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Antimicrobial functions of inflammasomes.
Chen KW, Schroder K. Chen KW, et al. Curr Opin Microbiol. 2013 Jun;16(3):311-8. doi: 10.1016/j.mib.2013.02.004. Epub 2013 Mar 4. Curr Opin Microbiol. 2013. PMID: 23466299 Review.
A novel flow cytometric method to assess inflammasome formation.
Sester DP, Thygesen SJ, Sagulenko V, Vajjhala PR, Cridland JA, Vitak N, Chen KW, Osborne GW, Schroder K, Stacey KJ. Sester DP, et al. Among authors: chen kw. J Immunol. 2015 Jan 1;194(1):455-62. doi: 10.4049/jimmunol.1401110. Epub 2014 Nov 17. J Immunol. 2015. PMID: 25404358
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.
Conos SA, Chen KW, De Nardo D, Hara H, Whitehead L, Núñez G, Masters SL, Murphy JM, Schroder K, Vaux DL, Lawlor KE, Lindqvist LM, Vince JE. Conos SA, et al. Among authors: chen kw. Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E961-E969. doi: 10.1073/pnas.1613305114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096356 Free PMC article.
XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation.
Lawlor KE, Feltham R, Yabal M, Conos SA, Chen KW, Ziehe S, Graß C, Zhan Y, Nguyen TA, Hall C, Vince AJ, Chatfield SM, D'Silva DB, Pang KC, Schroder K, Silke J, Vaux DL, Jost PJ, Vince JE. Lawlor KE, et al. Among authors: chen kw. Cell Rep. 2017 Jul 18;20(3):668-682. doi: 10.1016/j.celrep.2017.06.073. Cell Rep. 2017. PMID: 28723569 Free article.
Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.
Boucher D, Monteleone M, Coll RC, Chen KW, Ross CM, Teo JL, Gomez GA, Holley CL, Bierschenk D, Stacey KJ, Yap AS, Bezbradica JS, Schroder K. Boucher D, et al. Among authors: chen kw. J Exp Med. 2018 Mar 5;215(3):827-840. doi: 10.1084/jem.20172222. Epub 2018 Feb 6. J Exp Med. 2018. PMID: 29432122 Free PMC article.
421 results