Chen W - Search Results

1

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.

Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, Berman DM, Jenuwein T, Pruitt K, Sharkis SJ, Watkins DN, Herman JG, Baylin SB. Ohm JE, et al. Among authors: chen w. Nat Genet. 2007 Feb;39(2):237-42. doi: 10.1038/ng1972. Epub 2007 Jan 9. Nat Genet. 2007. PMID: 17211412 Free PMC article.

2

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.

Suzuki H, Watkins DN, Jair KW, Schuebel KE, Markowitz SD, Chen WD, Pretlow TP, Yang B, Akiyama Y, Van Engeland M, Toyota M, Tokino T, Hinoda Y, Imai K, Herman JG, Baylin SB. Suzuki H, et al. Nat Genet. 2004 Apr;36(4):417-22. doi: 10.1038/ng1330. Epub 2004 Mar 14. Nat Genet. 2004. PMID: 15034581

3

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer.

Suzuki H, Gabrielson E, Chen W, Anbazhagan R, van Engeland M, Weijenberg MP, Herman JG, Baylin SB. Suzuki H, et al. Among authors: chen w. Nat Genet. 2002 Jun;31(2):141-9. doi: 10.1038/ng892. Epub 2002 May 6. Nat Genet. 2002. PMID: 11992124

4

CIMPle origin for promoter hypermethylation in colorectal cancer?

Schuebel K, Chen W, Baylin SB. Schuebel K, et al. Among authors: chen w. Nat Genet. 2006 Jul;38(7):738-40. doi: 10.1038/ng0706-738. Nat Genet. 2006. PMID: 16804535 No abstract available.

5

Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.

Schuebel KE, Chen W, Cope L, Glöckner SC, Suzuki H, Yi JM, Chan TA, Van Neste L, Van Criekinge W, van den Bosch S, van Engeland M, Ting AH, Jair K, Yu W, Toyota M, Imai K, Ahuja N, Herman JG, Baylin SB. Schuebel KE, et al. Among authors: chen w. PLoS Genet. 2007 Sep;3(9):1709-23. doi: 10.1371/journal.pgen.0030157. Epub 2007 Jul 31. PLoS Genet. 2007. PMID: 17892325 Free PMC article.

6

Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis.

Chan TA, Glockner S, Yi JM, Chen W, Van Neste L, Cope L, Herman JG, Velculescu V, Schuebel KE, Ahuja N, Baylin SB. Chan TA, et al. Among authors: chen w. PLoS Med. 2008 May 27;5(5):e114. doi: 10.1371/journal.pmed.0050114. PLoS Med. 2008. PMID: 18507500 Free PMC article.

7

Sensitive digital quantification of DNA methylation in clinical samples.

Li M, Chen WD, Papadopoulos N, Goodman SN, Bjerregaard NC, Laurberg S, Levin B, Juhl H, Arber N, Moinova H, Durkee K, Schmidt K, He Y, Diehl F, Velculescu VE, Zhou S, Diaz LA Jr, Kinzler KW, Markowitz SD, Vogelstein B. Li M, et al. Among authors: chen wd. Nat Biotechnol. 2009 Sep;27(9):858-63. doi: 10.1038/nbt.1559. Epub 2009 Aug 16. Nat Biotechnol. 2009. PMID: 19684580 Free PMC article.

8

HLTF gene silencing in human colon cancer.

Moinova HR, Chen WD, Shen L, Smiraglia D, Olechnowicz J, Ravi L, Kasturi L, Myeroff L, Plass C, Parsons R, Minna J, Willson JK, Green SB, Issa JP, Markowitz SD. Moinova HR, et al. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4562-7. doi: 10.1073/pnas.062459899. Epub 2002 Mar 19. Proc Natl Acad Sci U S A. 2002. PMID: 11904375 Free PMC article.

9

MMTV promoter hypomethylation is linked to spontaneous and MNU associated c-neu expression and mammary carcinogenesis in MMTV c-neu transgenic mice.

Zhou H, Chen WD, Qin X, Lee K, Liu L, Markowitz SD, Gerson SL. Zhou H, et al. Among authors: chen wd. Oncogene. 2001 Sep 20;20(42):6009-17. doi: 10.1038/sj.onc.1204830. Oncogene. 2001. PMID: 11593408

10

Detection in fecal DNA of colon cancer-specific methylation of the nonexpressed vimentin gene.

Chen WD, Han ZJ, Skoletsky J, Olson J, Sah J, Myeroff L, Platzer P, Lu S, Dawson D, Willis J, Pretlow TP, Lutterbaugh J, Kasturi L, Willson JK, Rao JS, Shuber A, Markowitz SD. Chen WD, et al. J Natl Cancer Inst. 2005 Aug 3;97(15):1124-32. doi: 10.1093/jnci/dji204. J Natl Cancer Inst. 2005. PMID: 16077070

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