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Pancreatic cancer cells upregulate LPAR4 in response to isolation stress to promote an ECM-enriched niche and support tumour initiation.
Wu C, Rakhshandehroo T, Wettersten HI, Campos A, von Schalscha T, Jain S, Yu Z, Tan J, Mose E, Childers BG, Lowy AM, Weis SM, Cheresh DA. Wu C, et al. Among authors: cheresh da. Nat Cell Biol. 2023 Feb;25(2):309-322. doi: 10.1038/s41556-022-01055-y. Epub 2023 Jan 16. Nat Cell Biol. 2023. PMID: 36646789 Free PMC article.
Agonizing integrin antagonists?
Weis SM, Stupack DG, Cheresh DA. Weis SM, et al. Among authors: cheresh da. Cancer Cell. 2009 May 5;15(5):359-61. doi: 10.1016/j.ccr.2009.04.005. Cancer Cell. 2009. PMID: 19411065 Free article.
αV integrins in angiogenesis and cancer.
Weis SM, Cheresh DA. Weis SM, et al. Among authors: cheresh da. Cold Spring Harb Perspect Med. 2011 Sep;1(1):a006478. doi: 10.1101/cshperspect.a006478. Cold Spring Harb Perspect Med. 2011. PMID: 22229119 Free PMC article. Review.
A wake-up call for hibernating tumour cells.
Weis SM, Cheresh DA. Weis SM, et al. Among authors: cheresh da. Nat Cell Biol. 2013 Jul;15(7):721-3. doi: 10.1038/ncb2794. Nat Cell Biol. 2013. PMID: 23817234
An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, Lippman SM, Desgrosellier JS, Anand S, Weis SM, Cheresh DA. Seguin L, et al. Among authors: cheresh da. Nat Cell Biol. 2014 May;16(5):457-68. doi: 10.1038/ncb2953. Epub 2014 Apr 20. Nat Cell Biol. 2014. PMID: 24747441 Free PMC article.
232 results