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TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.
Biroccio A, Cherfils-Vicini J, Augereau A, Pinte S, Bauwens S, Ye J, Simonet T, Horard B, Jamet K, Cervera L, Mendez-Bermudez A, Poncet D, Grataroli R, de Rodenbeeke CT, Salvati E, Rizzo A, Zizza P, Ricoul M, Cognet C, Kuilman T, Duret H, Lépinasse F, Marvel J, Verhoeyen E, Cosset FL, Peeper D, Smyth MJ, Londoño-Vallejo A, Sabatier L, Picco V, Pages G, Scoazec JY, Stoppacciaro A, Leonetti C, Vivier E, Gilson E. Biroccio A, et al. Nat Cell Biol. 2013 Jul;15(7):818-28. doi: 10.1038/ncb2774. Epub 2013 Jun 23. Nat Cell Biol. 2013. PMID: 23792691
TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection.
Benarroch-Popivker D, Pisano S, Mendez-Bermudez A, Lototska L, Kaur P, Bauwens S, Djerbi N, Latrick CM, Fraisier V, Pei B, Gay A, Jaune E, Foucher K, Cherfils-Vicini J, Aeby E, Miron S, Londoño-Vallejo A, Ye J, Le Du MH, Wang H, Gilson E, Giraud-Panis MJ. Benarroch-Popivker D, et al. Mol Cell. 2016 Jan 21;61(2):274-86. doi: 10.1016/j.molcel.2015.12.009. Epub 2016 Jan 7. Mol Cell. 2016. PMID: 26774283 Free PMC article.
Cancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein TRF2.
Cherfils-Vicini J, Iltis C, Cervera L, Pisano S, Croce O, Sadouni N, Győrffy B, Collet R, Renault VM, Rey-Millet M, Leonetti C, Zizza P, Allain F, Ghiringhelli F, Soubeiran N, Shkreli M, Vivier E, Biroccio A, Gilson E. Cherfils-Vicini J, et al. EMBO J. 2019 Jun 3;38(11):e100012. doi: 10.15252/embj.2018100012. Epub 2019 Apr 18. EMBO J. 2019. PMID: 31000523 Free PMC article.
[Longevity clocks: The promoting role of telomeres?].
Cherfils-Vicini J, Gilson É. Cherfils-Vicini J, et al. Med Sci (Paris). 2020 Dec;36(12):1113-1117. doi: 10.1051/medsci/2020242. Epub 2020 Dec 9. Med Sci (Paris). 2020. PMID: 33296627 Free article. Review. French.
24 results