Chester KA - Search Results

1

The role of extracellular spacer regions in the optimal design of chimeric immune receptors: evaluation of four different scFvs and antigens.

Guest RD, Hawkins RE, Kirillova N, Cheadle EJ, Arnold J, O'Neill A, Irlam J, Chester KA, Kemshead JT, Shaw DM, Embleton MJ, Stern PL, Gilham DE. Guest RD, et al. Among authors: chester ka. J Immunother. 2005 May-Jun;28(3):203-11. doi: 10.1097/01.cji.0000161397.96582.59. J Immunother. 2005. PMID: 15838376

2

The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity.

Thistlethwaite FC, Gilham DE, Guest RD, Rothwell DG, Pillai M, Burt DJ, Byatte AJ, Kirillova N, Valle JW, Sharma SK, Chester KA, Westwood NB, Halford SER, Nabarro S, Wan S, Austin E, Hawkins RE. Thistlethwaite FC, et al. Among authors: chester ka. Cancer Immunol Immunother. 2017 Nov;66(11):1425-1436. doi: 10.1007/s00262-017-2034-7. Epub 2017 Jun 28. Cancer Immunol Immunother. 2017. PMID: 28660319 Free PMC article. Clinical Trial.

3

Clinical issues in antibody design.

Chester KA, Hawkins RE. Chester KA, et al. Trends Biotechnol. 1995 Aug;13(8):294-300. doi: 10.1016/S0167-7799(00)88968-4. Trends Biotechnol. 1995. PMID: 7662305 Review.

4

Antibody-directed enzyme-prodrug therapy.

Pedley RB, Sharma SK, Hawkins RE, Chester KA. Pedley RB, et al. Among authors: chester ka. Methods Mol Med. 2004;90:491-514. doi: 10.1385/1-59259-429-8:491. Methods Mol Med. 2004. PMID: 14657581 No abstract available.

5

Production and tumour-binding characterization of a chimeric anti-CEA Fab expressed in Escherichia coli.

Chester KA, Robson L, Keep PA, Pedley RB, Boden JA, Boxer GM, Hawkins RE, Begent RH. Chester KA, et al. Int J Cancer. 1994 Apr 1;57(1):67-72. doi: 10.1002/ijc.2910570113. Int J Cancer. 1994. PMID: 8150543

6

A single chain Fv derived from a filamentous phage library has distinct tumor targeting advantages over one derived from a hybridoma.

Verhaar MJ, Chester KA, Keep PA, Robson L, Pedley RB, Boden JA, Hawkins RE, Begent RH. Verhaar MJ, et al. Among authors: chester ka. Int J Cancer. 1995 May 16;61(4):497-501. doi: 10.1002/ijc.2910610412. Int J Cancer. 1995. PMID: 7759155

7

Purification of bacterially expressed single chain Fv antibodies for clinical applications using metal chelate chromatography.

Casey JL, Keep PA, Chester KA, Robson L, Hawkins RE, Begent RH. Casey JL, et al. Among authors: chester ka. J Immunol Methods. 1995 Feb 13;179(1):105-16. doi: 10.1016/0022-1759(94)00278-5. J Immunol Methods. 1995. PMID: 7868918

8

Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library.

Begent RH, Verhaar MJ, Chester KA, Casey JL, Green AJ, Napier MP, Hope-Stone LD, Cushen N, Keep PA, Johnson CJ, Hawkins RE, Hilson AJ, Robson L. Begent RH, et al. Among authors: chester ka. Nat Med. 1996 Sep;2(9):979-84. doi: 10.1038/nm0996-979. Nat Med. 1996. PMID: 8782454 Clinical Trial.

9

Technetium-99m radiolabeling using a phage-derived single-chain Fv with a C-terminal cysteine.

Verhaar MJ, Keep PA, Hawkins RE, Robson L, Casey JL, Pedley B, Boden JA, Begent RH, Chester KA. Verhaar MJ, et al. Among authors: chester ka. J Nucl Med. 1996 May;37(5):868-72. J Nucl Med. 1996. PMID: 8965166 Free article.

10

Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus.

Kogelberg H, Tolner B, Thomas GJ, Di Cara D, Minogue S, Ramesh B, Sodha S, Marsh D, Lowdell MW, Meyer T, Begent RH, Hart I, Marshall JF, Chester K. Kogelberg H, et al. J Mol Biol. 2008 Oct 3;382(2):385-401. doi: 10.1016/j.jmb.2008.07.013. Epub 2008 Jul 16. J Mol Biol. 2008. PMID: 18656482 Free PMC article.

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