Chi B - Search Results

1

A U2-snRNP-independent role of SF3b in promoting mRNA export.

Wang K, Yin C, Du X, Chen S, Wang J, Zhang L, Wang L, Yu Y, Chi B, Shi M, Wang C, Reed R, Zhou Y, Huang J, Cheng H. Wang K, et al. Among authors: chi b. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7837-7846. doi: 10.1073/pnas.1818835116. Epub 2019 Mar 28. Proc Natl Acad Sci U S A. 2019. PMID: 30923118 Free PMC article.

2

Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNA.

Chi B, Wang Q, Wu G, Tan M, Wang L, Shi M, Chang X, Cheng H. Chi B, et al. Nucleic Acids Res. 2013 Jan;41(2):1294-306. doi: 10.1093/nar/gks1188. Epub 2012 Dec 7. Nucleic Acids Res. 2013. PMID: 23222130 Free PMC article.

3

A Sub-Element in PRE enhances nuclear export of intronless mRNAs by recruiting the TREX complex via ZC3H18.

Chi B, Wang K, Du Y, Gui B, Chang X, Wang L, Fan J, Chen S, Wu X, Li G, Cheng H. Chi B, et al. Nucleic Acids Res. 2014 Jun;42(11):7305-18. doi: 10.1093/nar/gku350. Epub 2014 Apr 29. Nucleic Acids Res. 2014. PMID: 24782531 Free PMC article.

4

U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish.

Yu Y, Chi B, Xia W, Gangopadhyay J, Yamazaki T, Winkelbauer-Hurt ME, Yin S, Eliasse Y, Adams E, Shaw CE, Reed R. Yu Y, et al. Among authors: chi b. Nucleic Acids Res. 2015 Mar 31;43(6):3208-18. doi: 10.1093/nar/gkv157. Epub 2015 Mar 3. Nucleic Acids Res. 2015. PMID: 25735748 Free PMC article.

5

Exosome cofactor hMTR4 competes with export adaptor ALYREF to ensure balanced nuclear RNA pools for degradation and export.

Fan J, Kuai B, Wu G, Wu X, Chi B, Wang L, Wang K, Shi Z, Zhang H, Chen S, He Z, Wang S, Zhou Z, Li G, Cheng H. Fan J, et al. Among authors: chi b. EMBO J. 2017 Oct 2;36(19):2870-2886. doi: 10.15252/embj.201696139. Epub 2017 Aug 11. EMBO J. 2017. PMID: 28801509 Free PMC article.

6

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

Chi B, O'Connell JD, Yamazaki T, Gangopadhyay J, Gygi SP, Reed R. Chi B, et al. Sci Rep. 2018 Jun 8;8(1):8755. doi: 10.1038/s41598-018-27136-3. Sci Rep. 2018. PMID: 29884807 Free PMC article.

7

mRNAs are sorted for export or degradation before passing through nuclear speckles.

Fan J, Kuai B, Wang K, Wang L, Wang Y, Wu X, Chi B, Li G, Cheng H. Fan J, et al. Among authors: chi b. Nucleic Acids Res. 2018 Sep 19;46(16):8404-8416. doi: 10.1093/nar/gky650. Nucleic Acids Res. 2018. PMID: 30032211 Free PMC article.

8

The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex.

Chi B, O'Connell JD, Iocolano AD, Coady JA, Yu Y, Gangopadhyay J, Gygi SP, Reed R. Chi B, et al. Nucleic Acids Res. 2018 Dec 14;46(22):11939-11951. doi: 10.1093/nar/gky1093. Nucleic Acids Res. 2018. PMID: 30398641 Free PMC article.

9

NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.

Wang J, Chen J, Wu G, Zhang H, Du X, Chen S, Zhang L, Wang K, Fan J, Gao S, Wu X, Zhang S, Kuai B, Zhao P, Chi B, Wang L, Li G, Wong CCL, Zhou Y, Li J, Yun C, Cheng H. Wang J, et al. Among authors: chi b. Genes Dev. 2019 May 1;33(9-10):536-549. doi: 10.1101/gad.322602.118. Epub 2019 Mar 6. Genes Dev. 2019. PMID: 30842217 Free PMC article.

10

Causal ALS genes impact the MHC class II antigen presentation pathway.

Chi B, Öztürk MM, Paraggio CL, Leonard CE, Sanita ME, Dastpak M, O'Connell JD, Coady JA, Zhang J, Gygi SP, Lopez-Gonzalez R, Yin S, Reed R. Chi B, et al. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2305756120. doi: 10.1073/pnas.2305756120. Epub 2023 Sep 18. Proc Natl Acad Sci U S A. 2023. PMID: 37722062 Free PMC article.

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