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Intestinal FFA2 promotes obesity by altering food intake in Western diet-fed mice.
Lednovich KR, Gough S, Priyadarshini M, Pandya N, Nnyamah C, Xu K, Wicksteed B, Mishra S, Jain S, Zapater JL, Cordoba-Chacon J, Yadav H, Layden BT. Lednovich KR, et al. Among authors: nnyamah c. J Endocrinol. 2024 Jan 11;260(2):e230184. doi: 10.1530/JOE-23-0184. Print 2024 Feb 1. J Endocrinol. 2024. PMID: 38032704 Free PMC article.
Intestinal FFA3 mediates obesogenic effects in mice on a Western diet.
Lednovich KR, Nnyamah C, Gough S, Priyadarshini M, Xu K, Wicksteed B, Mishra S, Jain S, Zapater JL, Yadav H, Layden BT. Lednovich KR, et al. Among authors: nnyamah c. Am J Physiol Endocrinol Metab. 2022 Sep 1;323(3):E290-E306. doi: 10.1152/ajpendo.00016.2022. Epub 2022 Jul 20. Am J Physiol Endocrinol Metab. 2022. PMID: 35858247 Free PMC article.
β cell acetate production and release are negligible.
Xu K, Nnyamah C, Pandya N, Sweis N, Corona-Avila I, Priyadarshini M, Wicksteed B, Layden BT. Xu K, et al. Among authors: nnyamah c. Islets. 2024 Dec 31;16(1):2339558. doi: 10.1080/19382014.2024.2339558. Epub 2024 Apr 12. Islets. 2024. PMID: 38607959 Free PMC article.