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Page 1
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Cell. 2021 Feb 4;184(3):655-674.e27. doi: 10.1016/j.cell.2020.12.024. Epub 2021 Jan 25.
Cell. 2021.
PMID: 33497611
Free PMC article.
Drug repurposing for Dravet syndrome in scn1Lab-/- mutant zebrafish.
Sourbron J, Partoens M, Scheldeman C, Zhang Y, Lagae L, de Witte P.
Sourbron J, et al. Among authors: scheldeman c.
Epilepsia. 2019 Feb;60(2):e8-e13. doi: 10.1111/epi.14647. Epub 2019 Jan 20.
Epilepsia. 2019.
PMID: 30663052
Free PMC article.
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Cannabidiol modulates phosphorylated rpS6 signalling in a zebrafish model of Tuberous Sclerosis Complex.
Serra I, Scheldeman C, Bazelot M, Whalley BJ, Dallas ML, de Witte PAM, Williams CM.
Serra I, et al. Among authors: scheldeman c.
Behav Brain Res. 2019 May 2;363:135-144. doi: 10.1016/j.bbr.2019.01.040. Epub 2019 Jan 23.
Behav Brain Res. 2019.
PMID: 30684511
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mTOR-related neuropathology in mutant tsc2 zebrafish: Phenotypic, transcriptomic and pharmacological analysis.
Scheldeman C, Mills JD, Siekierska A, Serra I, Copmans D, Iyer AM, Whalley BJ, Maes J, Jansen AC, Lagae L, Aronica E, de Witte PAM.
Scheldeman C, et al.
Neurobiol Dis. 2017 Dec;108:225-237. doi: 10.1016/j.nbd.2017.09.004. Epub 2017 Sep 6.
Neurobiol Dis. 2017.
PMID: 28888969
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Gain-of-function FHF1 mutation causes early-onset epileptic encephalopathy with cerebellar atrophy.
Siekierska A, Isrie M, Liu Y, Scheldeman C, Vanthillo N, Lagae L, de Witte PA, Van Esch H, Goldfarb M, Buyse GM.
Siekierska A, et al. Among authors: scheldeman c.
Neurology. 2016 Jun 7;86(23):2162-70. doi: 10.1212/WNL.0000000000002752. Epub 2016 May 4.
Neurology. 2016.
PMID: 27164707
Free PMC article.
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