Christian Landles[Author] - Search Results

Year	Number of Results
2003	1
2004	1
2005	1
2006	1
2007	2
2008	1
2010	3
2011	1
2012	2
2013	3
2017	2
2019	1
2020	2
2021	2
2022	1
2023	1
2024	1

1

Alternative processing of human HTT mRNA with implications for Huntington's disease therapeutics.

Fienko S, Landles C, Sathasivam K, McAteer SJ, Milton RE, Osborne GF, Smith EJ, Jones ST, Bondulich MK, Danby ECE, Phillips J, Taxy BA, Kordasiewicz HB, Bates GP. Fienko S, et al. Among authors: landles c. Brain. 2022 Dec 19;145(12):4409-4424. doi: 10.1093/brain/awac241. Brain. 2022. PMID: 35793238 Free PMC article.

2

A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease.

Aldous SG, Smith EJ, Landles C, Osborne GF, Cañibano-Pico M, Nita IM, Phillips J, Zhang Y, Jin B, Hirst MB, Benn CL, Bond BC, Edelmann W, Greene JR, Bates GP. Aldous SG, et al. Among authors: landles c. Brain. 2024 May 3;147(5):1784-1798. doi: 10.1093/brain/awae063. Brain. 2024. PMID: 38387080 Free PMC article.

3

Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches.

Smith EJ, Sathasivam K, Landles C, Osborne GF, Mason MA, Gomez-Paredes C, Taxy BA, Milton RE, Ast A, Schindler F, Zhang C, Duan W, Wanker EE, Bates GP. Smith EJ, et al. Among authors: landles c. Brain Commun. 2023 Jan 20;5(1):fcad010. doi: 10.1093/braincomms/fcad010. eCollection 2023. Brain Commun. 2023. PMID: 36756307 Free PMC article.

4

Huntingtin and the molecular pathogenesis of Huntington's disease. Fourth in molecular medicine review series.

Landles C, Bates GP. Landles C, et al. EMBO Rep. 2004 Oct;5(10):958-63. doi: 10.1038/sj.embor.7400250. EMBO Rep. 2004. PMID: 15459747 Free PMC article. Review.

5

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models.

Hegde RN, Chiki A, Petricca L, Martufi P, Arbez N, Mouchiroud L, Auwerx J, Landles C, Bates GP, Singh-Bains MK, Dragunow M, Curtis MA, Faull RL, Ross CA, Caricasole A, Lashuel HA. Hegde RN, et al. Among authors: landles c. EMBO J. 2020 Sep 1;39(17):e104671. doi: 10.15252/embj.2020104671. Epub 2020 Aug 5. EMBO J. 2020. PMID: 32757223 Free PMC article.

6

Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice.

Bryant DT, Landles C, Papadopoulou AS, Benjamin AC, Duckworth JK, Rosahl T, Benn CL, Bates GP. Bryant DT, et al. Among authors: landles c. Sci Rep. 2017 Sep 19;7(1):11900. doi: 10.1038/s41598-017-11630-1. Sci Rep. 2017. PMID: 28928414 Free PMC article.

7

Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington's disease.

Zhou Y, Peskett TR, Landles C, Warner JB, Sathasivam K, Smith EJ, Chen S, Wetzel R, Lashuel HA, Bates GP, Saibil HR. Zhou Y, et al. Among authors: landles c. Acta Neuropathol Commun. 2021 Apr 14;9(1):70. doi: 10.1186/s40478-021-01172-z. Acta Neuropathol Commun. 2021. PMID: 33853668 Free PMC article.

8

Development of novel bioassays to detect soluble and aggregated Huntingtin proteins on three technology platforms.

Landles C, Milton RE, Jean A, McLarnon S, McAteer SJ, Taxy BA, Osborne GF, Zhang C, Duan W, Howland D, Bates GP. Landles C, et al. Brain Commun. 2021 Jan 5;3(1):fcaa231. doi: 10.1093/braincomms/fcaa231. eCollection 2021. Brain Commun. 2021. PMID: 33604571 Free PMC article.

9

Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression.

Weiss A, Träger U, Wild EJ, Grueninger S, Farmer R, Landles C, Scahill RI, Lahiri N, Haider S, Macdonald D, Frost C, Bates GP, Bilbe G, Kuhn R, Andre R, Tabrizi SJ. Weiss A, et al. Among authors: landles c. J Clin Invest. 2012 Oct;122(10):3731-6. doi: 10.1172/JCI64565. Epub 2012 Sep 17. J Clin Invest. 2012. PMID: 22996692 Free PMC article.

10

The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patients.

Neueder A, Landles C, Ghosh R, Howland D, Myers RH, Faull RLM, Tabrizi SJ, Bates GP. Neueder A, et al. Among authors: landles c. Sci Rep. 2017 May 2;7(1):1307. doi: 10.1038/s41598-017-01510-z. Sci Rep. 2017. PMID: 28465506 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

25 results

Results by year

Search Page

Filters

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

Search Results

25 results

Results by year