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G6PD activity contributes to the regulation of histone acetylation and gene expression in smooth muscle cells and to the pathogenesis of vascular diseases.
Dhagia V, Kitagawa A, Jacob C, Zheng C, D'Alessandro A, Edwards JG, Rocic P, Gupte R, Gupte SA. Dhagia V, et al. Among authors: jacob c. Am J Physiol Heart Circ Physiol. 2021 Mar 1;320(3):H999-H1016. doi: 10.1152/ajpheart.00488.2020. Epub 2021 Jan 8. Am J Physiol Heart Circ Physiol. 2021. PMID: 33416454 Free PMC article.
CRISPR-Mediated Single Nucleotide Polymorphism Modeling in Rats Reveals Insight Into Reduced Cardiovascular Risk Associated With Mediterranean G6PD Variant.
Kitagawa A, Kizub I, Jacob C, Michael K, D'Alessandro A, Reisz JA, Grzybowski M, Geurts AM, Rocic P, Gupte R, Miano JM, Gupte SA. Kitagawa A, et al. Among authors: jacob c. Hypertension. 2020 Aug;76(2):523-532. doi: 10.1161/HYPERTENSIONAHA.120.14772. Epub 2020 Jun 8. Hypertension. 2020. PMID: 32507041 Free PMC article.
Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation.
Joshi SR, Kitagawa A, Jacob C, Hashimoto R, Dhagia V, Ramesh A, Zheng C, Zhang H, Jordan A, Waddell I, Leopold J, Hu CJ, McMurtry IF, D'Alessandro A, Stenmark KR, Gupte SA. Joshi SR, et al. Among authors: jacob c. Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1;318(4):L773-L786. doi: 10.1152/ajplung.00001.2020. Epub 2020 Mar 11. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32159369 Free PMC article.
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