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Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis.
Papadopoulou D, Roumelioti F, Tzaferis C, Chouvardas P, Pedersen AK, Charalampous F, Christodoulou-Vafeiadou E, Ntari L, Karagianni N, Denis MC, Olsen JV, Matralis AN, Kollias G. Papadopoulou D, et al. Among authors: christodoulou vafeiadou e. JCI Insight. 2023 May 8;8(9):e165024. doi: 10.1172/jci.insight.165024. JCI Insight. 2023. PMID: 37014697 Free PMC article.
Transmembrane TNF drives osteoproliferative joint inflammation reminiscent of human spondyloarthritis.
Kaaij MH, van Tok MN, Blijdorp IC, Ambarus CA, Stock M, Pots D, Knaup VL, Armaka M, Christodoulou-Vafeiadou E, van Melsen TK, Masdar H, Eskes HJPP, Yeremenko NG, Kollias G, Schett G, Tas SW, van Duivenvoorde LM, Baeten DLP. Kaaij MH, et al. Among authors: christodoulou vafeiadou e. J Exp Med. 2020 Oct 5;217(10):e20200288. doi: 10.1084/jem.20200288. J Exp Med. 2020. PMID: 32662821 Free PMC article.
Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment.
Ntari L, Nikolaou C, Kranidioti K, Papadopoulou D, Christodoulou-Vafeiadou E, Chouvardas P, Meier F, Geka C, Denis MC, Karagianni N, Kollias G. Ntari L, et al. Among authors: christodoulou vafeiadou e. J Transl Med. 2021 Apr 23;19(1):165. doi: 10.1186/s12967-021-02764-y. J Transl Med. 2021. PMID: 33892739 Free PMC article.