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Single-sequence protein structure prediction using a language model and deep learning.
Chowdhury R, Bouatta N, Biswas S, Floristean C, Kharkar A, Roy K, Rochereau C, Ahdritz G, Zhang J, Church GM, Sorger PK, AlQuraishi M. Chowdhury R, et al. Among authors: church gm. Nat Biotechnol. 2022 Nov;40(11):1617-1623. doi: 10.1038/s41587-022-01432-w. Epub 2022 Oct 3. Nat Biotechnol. 2022. PMID: 36192636 Free PMC article.
Engineered Living Materials For Sustainability.
An B, Wang Y, Huang Y, Wang X, Liu Y, Xun D, Church GM, Dai Z, Yi X, Tang TC, Zhong C. An B, et al. Among authors: church gm. Chem Rev. 2023 Mar 8;123(5):2349-2419. doi: 10.1021/acs.chemrev.2c00512. Epub 2022 Dec 13. Chem Rev. 2023. PMID: 36512650 Review.
Engineering Ca2+-Dependent DNA Polymerase Activity.
Biggs BW, de Paz AM, Bhan NJ, Cybulski TR, Church GM, Tyo KEJ. Biggs BW, et al. Among authors: church gm. ACS Synth Biol. 2023 Nov 17;12(11):3301-3311. doi: 10.1021/acssynbio.3c00302. Epub 2023 Oct 19. ACS Synth Biol. 2023. PMID: 37856140
Deep diversification of an AAV capsid protein by machine learning.
Bryant DH, Bashir A, Sinai S, Jain NK, Ogden PJ, Riley PF, Church GM, Colwell LJ, Kelsic ED. Bryant DH, et al. Among authors: church gm. Nat Biotechnol. 2021 Jun;39(6):691-696. doi: 10.1038/s41587-020-00793-4. Epub 2021 Feb 11. Nat Biotechnol. 2021. PMID: 33574611
Low-N protein engineering with data-efficient deep learning.
Biswas S, Khimulya G, Alley EC, Esvelt KM, Church GM. Biswas S, et al. Among authors: church gm. Nat Methods. 2021 Apr;18(4):389-396. doi: 10.1038/s41592-021-01100-y. Epub 2021 Apr 7. Nat Methods. 2021. PMID: 33828272
595 results