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CRK proteins selectively regulate T cell migration into inflamed tissues.
Huang Y, Clarke F, Karimi M, Roy NH, Williamson EK, Okumura M, Mochizuki K, Chen EJ, Park TJ, Debes GF, Zhang Y, Curran T, Kambayashi T, Burkhardt JK. Huang Y, et al. Among authors: clarke f. J Clin Invest. 2015 Mar 2;125(3):1019-32. doi: 10.1172/JCI77278. Epub 2015 Jan 26. J Clin Invest. 2015. PMID: 25621495 Free PMC article.
Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cells.
Dehring DA, Clarke F, Ricart BG, Huang Y, Gomez TS, Williamson EK, Hammer DA, Billadeau DD, Argon Y, Burkhardt JK. Dehring DA, et al. Among authors: clarke f. J Immunol. 2011 Apr 15;186(8):4805-18. doi: 10.4049/jimmunol.1003102. Epub 2011 Mar 11. J Immunol. 2011. PMID: 21398607 Free PMC article.
Protein tyrosine phosphatase PTPN22 regulates LFA-1 dependent Th1 responses.
Sanchez-Blanco C, Clarke F, Cornish GH, Depoil D, Thompson SJ, Dai X, Rawlings DJ, Dustin ML, Zamoyska R, Cope AP, Purvis HA. Sanchez-Blanco C, et al. Among authors: clarke f. J Autoimmun. 2018 Nov;94:45-55. doi: 10.1016/j.jaut.2018.07.008. Epub 2018 Jul 24. J Autoimmun. 2018. PMID: 30054208 Free PMC article.
Superresolution imaging of the cytoplasmic phosphatase PTPN22 links integrin-mediated T cell adhesion with autoimmunity.
Burn GL, Cornish GH, Potrzebowska K, Samuelsson M, Griffié J, Minoughan S, Yates M, Ashdown G, Pernodet N, Morrison VL, Sanchez-Blanco C, Purvis H, Clarke F, Brownlie RJ, Vyse TJ, Zamoyska R, Owen DM, Svensson LM, Cope AP. Burn GL, et al. Among authors: clarke f. Sci Signal. 2016 Oct 4;9(448):ra99. doi: 10.1126/scisignal.aaf2195. Sci Signal. 2016. PMID: 27703032
397 results