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Page 1
Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC-derived models of Alzheimer's disease.
J Neurochem. 2023 Dec 8. doi: 10.1111/jnc.16014. Online ahead of print.
J Neurochem. 2023.
PMID: 38063257
Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3.
Chandrasekaran A, Dittlau KS, Corsi GI, Haukedal H, Doncheva NT, Ramakrishna S, Ambardar S, Salcedo C, Schmidt SI, Zhang Y, Cirera S, Pihl M, Schmid B, Nielsen TT, Nielsen JE, Kolko M, Kobolák J, Dinnyés A, Hyttel P, Palakodeti D, Gorodkin J, Muddashetty RS, Meyer M, Aldana BI, Freude KK.
Chandrasekaran A, et al. Among authors: salcedo c.
Stem Cell Reports. 2021 Nov 9;16(11):2736-2751. doi: 10.1016/j.stemcr.2021.09.013. Epub 2021 Oct 21.
Stem Cell Reports. 2021.
PMID: 34678206
Free PMC article.
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Brain endothelial cells metabolize glutamate via glutamate dehydrogenase to replenish TCA-intermediates and produce ATP under hypoglycemic conditions.
Hinca SB, Salcedo C, Wagner A, Goldeman C, Sadat E, Aibar MMD, Maechler P, Brodin B, Aldana BI, Helms HCC.
Hinca SB, et al. Among authors: salcedo c.
J Neurochem. 2021 Jun;157(6):1861-1875. doi: 10.1111/jnc.15207. Epub 2020 Oct 25.
J Neurochem. 2021.
PMID: 33025588
Free article.
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Functional Metabolic Mapping Reveals Highly Active Branched-Chain Amino Acid Metabolism in Human Astrocytes, Which Is Impaired in iPSC-Derived Astrocytes in Alzheimer's Disease.
Salcedo C, Andersen JV, Vinten KT, Pinborg LH, Waagepetersen HS, Freude KK, Aldana BI.
Salcedo C, et al.
Front Aging Neurosci. 2021 Sep 17;13:736580. doi: 10.3389/fnagi.2021.736580. eCollection 2021.
Front Aging Neurosci. 2021.
PMID: 34603012
Free PMC article.
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Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease.
Salcedo C, Wagner A, Andersen JV, Vinten KT, Waagepetersen HS, Schousboe A, Freude KK, Aldana BI.
Salcedo C, et al.
Neurochem Res. 2021 Oct;46(10):2676-2686. doi: 10.1007/s11064-021-03276-3. Epub 2021 Mar 12.
Neurochem Res. 2021.
PMID: 33710537
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Effects of pre- and neonatal undernutrition on the kyphotic response and c-Fos activity in the caudal periaqueductal gray of primiparous lactating Wistar rats.
Salcedo C, Torrero C, Regalado M, Rubio L, Salas M.
Salcedo C, et al.
Physiol Behav. 2018 Mar 1;185:87-94. doi: 10.1016/j.physbeh.2017.12.020. Epub 2017 Dec 18.
Physiol Behav. 2018.
PMID: 29269226
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