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Co-expression of truncated and full-length tau induces severe neurotoxicity.
Ozcelik S, Sprenger F, Skachokova Z, Fraser G, Abramowski D, Clavaguera F, Probst A, Frank S, Müller M, Staufenbiel M, Goedert M, Tolnay M, Winkler DT. Ozcelik S, et al. Among authors: clavaguera f. Mol Psychiatry. 2016 Dec;21(12):1790-1798. doi: 10.1038/mp.2015.228. Epub 2016 Feb 2. Mol Psychiatry. 2016. PMID: 26830137 Free PMC article.
Transmission and spreading of tauopathy in transgenic mouse brain.
Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, Fraser G, Stalder AK, Beibel M, Staufenbiel M, Jucker M, Goedert M, Tolnay M. Clavaguera F, et al. Nat Cell Biol. 2009 Jul;11(7):909-13. doi: 10.1038/ncb1901. Epub 2009 Jun 7. Nat Cell Biol. 2009. PMID: 19503072 Free PMC article.
"Prion-like" templated misfolding in tauopathies.
Clavaguera F, Lavenir I, Falcon B, Frank S, Goedert M, Tolnay M. Clavaguera F, et al. Brain Pathol. 2013 May;23(3):342-9. doi: 10.1111/bpa.12044. Brain Pathol. 2013. PMID: 23587140 Free PMC article. Review.
Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice.
Ozcelik S, Fraser G, Castets P, Schaeffer V, Skachokova Z, Breu K, Clavaguera F, Sinnreich M, Kappos L, Goedert M, Tolnay M, Winkler DT. Ozcelik S, et al. Among authors: clavaguera f. PLoS One. 2013 May 7;8(5):e62459. doi: 10.1371/journal.pone.0062459. Print 2013. PLoS One. 2013. PMID: 23667480 Free PMC article.
Brain homogenates from human tauopathies induce tau inclusions in mouse brain.
Clavaguera F, Akatsu H, Fraser G, Crowther RA, Frank S, Hench J, Probst A, Winkler DT, Reichwald J, Staufenbiel M, Ghetti B, Goedert M, Tolnay M. Clavaguera F, et al. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9535-40. doi: 10.1073/pnas.1301175110. Epub 2013 May 20. Proc Natl Acad Sci U S A. 2013. PMID: 23690619 Free PMC article.
23 results