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A Phase 2 Randomized Trial Evaluating the Antiviral Activity and Safety of the Direct-Acting Antiviral Bemnifosbuvir in Ambulatory Patients with Mild or Moderate COVID-19 (MOONSONG Study).
Boffito M, Dolan E, Singh K, Holmes W, Wildum S, Horga A, Pietropaolo K, Zhou XJ, Clinch B, Collinson N, Ukachukwu V. Boffito M, et al. Among authors: clinch b. Microbiol Spectr. 2023 Aug 17;11(4):e0007723. doi: 10.1128/spectrum.00077-23. Epub 2023 Jun 20. Microbiol Spectr. 2023. PMID: 37338393 Free PMC article. Clinical Trial.
Baloxavir Marboxil Single-dose Treatment in Influenza-infected Children: A Randomized, Double-blind, Active Controlled Phase 3 Safety and Efficacy Trial (miniSTONE-2).
Baker J, Block SL, Matharu B, Burleigh Macutkiewicz L, Wildum S, Dimonaco S, Collinson N, Clinch B, Piedra PA. Baker J, et al. Among authors: clinch b. Pediatr Infect Dis J. 2020 Aug;39(8):700-705. doi: 10.1097/INF.0000000000002747. Pediatr Infect Dis J. 2020. PMID: 32516282 Free PMC article. Clinical Trial.
Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission.
Lee LYY, Zhou J, Frise R, Goldhill DH, Koszalka P, Mifsud EJ, Baba K, Noda T, Ando Y, Sato K, Yuki AI, Shishido T, Uehara T, Wildum S, Zwanziger E, Collinson N, Kuhlbusch K, Clinch B, Hurt AC, Barclay WS. Lee LYY, et al. Among authors: clinch b. PLoS Pathog. 2020 Apr 15;16(4):e1008395. doi: 10.1371/journal.ppat.1008395. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32294137 Free PMC article.
Combining baloxavir marboxil with standard-of-care neuraminidase inhibitor in patients hospitalised with severe influenza (FLAGSTONE): a randomised, parallel-group, double-blind, placebo-controlled, superiority trial.
Kumar D, Ison MG, Mira JP, Welte T, Hwan Ha J, Hui DS, Zhong N, Saito T, Katugampola L, Collinson N, Williams S, Wildum S, Ackrill A, Clinch B, Lee N. Kumar D, et al. Among authors: clinch b. Lancet Infect Dis. 2022 May;22(5):718-730. doi: 10.1016/S1473-3099(21)00469-2. Epub 2022 Jan 24. Lancet Infect Dis. 2022. PMID: 35085510 Clinical Trial.
Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model.
Lee LY, Zhou J, Koszalka P, Frise R, Farrukee R, Baba K, Miah S, Shishido T, Galiano M, Hashimoto T, Omoto S, Uehara T, Mifsud EJ, Collinson N, Kuhlbusch K, Clinch B, Wildum S, Barclay WS, Hurt AC. Lee LY, et al. Among authors: clinch b. PLoS Pathog. 2021 May 6;17(5):e1009527. doi: 10.1371/journal.ppat.1009527. eCollection 2021 May. PLoS Pathog. 2021. PMID: 33956888 Free PMC article.
Predictors of Seeking Care for Influenza-Like Illness in a Novel Digital Study.
Chawla D, Benitez A, Xu H, Whitehill V, Tadesse-Bell S, Shapiro A, Ramirez E, Scherer K, Foschini L, Drawnel F, Clinch B, Prunotto M, Ukachukwu V. Chawla D, et al. Among authors: clinch b. Open Forum Infect Dis. 2022 Dec 22;10(1):ofac675. doi: 10.1093/ofid/ofac675. eCollection 2023 Jan. Open Forum Infect Dis. 2022. PMID: 36686628 Free PMC article.
Safety, Resistance, and Efficacy Results from a Phase IIIb Study of Conventional- and Double-Dose Oseltamivir Regimens for Treatment of Influenza in Immunocompromised Patients.
Mitha E, Krivan G, Jacobs F, Nagler A, Alrabaa S, Mykietiuk A, Kenwright A, Le Pogam S, Clinch B, Vareikiene L. Mitha E, et al. Among authors: clinch b. Infect Dis Ther. 2019 Dec;8(4):613-626. doi: 10.1007/s40121-019-00271-8. Epub 2019 Oct 30. Infect Dis Ther. 2019. PMID: 31667696 Free PMC article.
Understanding the Impact of Resistance to Influenza Antivirals.
Holmes EC, Hurt AC, Dobbie Z, Clinch B, Oxford JS, Piedra PA. Holmes EC, et al. Among authors: clinch b. Clin Microbiol Rev. 2021 Feb 10;34(2):e00224-20. doi: 10.1128/CMR.00224-20. Print 2021 Mar 17. Clin Microbiol Rev. 2021. PMID: 33568554 Free PMC article. Review.
Viral Kinetics and Resistance Development in Children Treated with Neuraminidase Inhibitors: The Influenza Resistance Information Study (IRIS).
Roosenhoff R, Reed V, Kenwright A, Schutten M, Boucher CA, Monto A, Clinch B, Kumar D, Whitley R, Nguyen-Van-Tam JS, Osterhaus ADME, Fouchier RAM, Fraaij PLA. Roosenhoff R, et al. Among authors: clinch b. Clin Infect Dis. 2020 Aug 22;71(5):1186-1194. doi: 10.1093/cid/ciz939. Clin Infect Dis. 2020. PMID: 31560055 Free PMC article.
25 results