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Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.
Baillie JK, Bretherick A, Haley CS, Clohisey S, Gray A, Neyton LPA, Barrett J, Stahl EA, Tenesa A, Andersson R, Brown JB, Faulkner GJ, Lizio M, Schaefer U, Daub C, Itoh M, Kondo N, Lassmann T, Kawai J; IIBDGC Consortium; Mole D, Bajic VB, Heutink P, Rehli M, Kawaji H, Sandelin A, Suzuki H, Satsangi J, Wells CA, Hacohen N, Freeman TC, Hayashizaki Y, Carninci P, Forrest ARR, Hume DA. Baillie JK, et al. Among authors: clohisey s. PLoS Comput Biol. 2018 Mar 1;14(3):e1005934. doi: 10.1371/journal.pcbi.1005934. eCollection 2018 Mar. PLoS Comput Biol. 2018. PMID: 29494619 Free PMC article.
Macrophage colony-stimulating factor (CSF1) controls monocyte production and maturation and the steady-state size of the liver in pigs.
Sauter KA, Waddell LA, Lisowski ZM, Young R, Lefevre L, Davis GM, Clohisey SM, McCulloch M, Magowan E, Mabbott NA, Summers KM, Hume DA. Sauter KA, et al. Am J Physiol Gastrointest Liver Physiol. 2016 Sep 1;311(3):G533-47. doi: 10.1152/ajpgi.00116.2016. Epub 2016 Jul 21. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27445344 Free PMC article.
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection.
Li B, Clohisey SM, Chia BS, Wang B, Cui A, Eisenhaure T, Schweitzer LD, Hoover P, Parkinson NJ, Nachshon A, Smith N, Regan T, Farr D, Gutmann MU, Bukhari SI, Law A, Sangesland M, Gat-Viks I, Digard P, Vasudevan S, Lingwood D, Dockrell DH, Doench JG, Baillie JK, Hacohen N. Li B, et al. Among authors: clohisey sm. Nat Commun. 2020 Jan 9;11(1):164. doi: 10.1038/s41467-019-13965-x. Nat Commun. 2020. PMID: 31919360 Free PMC article.
Comprehensive Characterization of Transcriptional Activity during Influenza A Virus Infection Reveals Biases in Cap-Snatching of Host RNA Sequences.
Clohisey S, Parkinson N, Wang B, Bertin N, Wise H, Tomoiu A; FANTOM5 Consortium; Summers KM, Hendry RW, Carninci P, Forrest ARR, Hayashizaki Y, Digard P, Hume DA, Baillie JK. Clohisey S, et al. J Virol. 2020 May 4;94(10):e01720-19. doi: 10.1128/JVI.01720-19. Print 2020 May 4. J Virol. 2020. PMID: 32161175 Free PMC article.
The Transcriptional Network That Controls Growth Arrest and Macrophage Differentiation in the Human Myeloid Leukemia Cell Line THP-1.
Gažová I, Lefevre L, Bush SJ, Clohisey S, Arner E, de Hoon M, Severin J, van Duin L, Andersson R, Lengeling A, Hume DA, Summers KM. Gažová I, et al. Among authors: clohisey s. Front Cell Dev Biol. 2020 Jul 3;8:498. doi: 10.3389/fcell.2020.00498. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32719792 Free PMC article.
Genetic mechanisms of critical illness in COVID-19.
Pairo-Castineira E, Clohisey S, Klaric L, Bretherick AD, Rawlik K, Pasko D, Walker S, Parkinson N, Fourman MH, Russell CD, Furniss J, Richmond A, Gountouna E, Wrobel N, Harrison D, Wang B, Wu Y, Meynert A, Griffiths F, Oosthuyzen W, Kousathanas A, Moutsianas L, Yang Z, Zhai R, Zheng C, Grimes G, Beale R, Millar J, Shih B, Keating S, Zechner M, Haley C, Porteous DJ, Hayward C, Yang J, Knight J, Summers C, Shankar-Hari M, Klenerman P, Turtle L, Ho A, Moore SC, Hinds C, Horby P, Nichol A, Maslove D, Ling L, McAuley D, Montgomery H, Walsh T, Pereira AC, Renieri A; GenOMICC Investigators; ISARIC4C Investigators; COVID-19 Human Genetics Initiative; 23andMe Investigators; BRACOVID Investigators; Gen-COVID Investigators; Shen X, Ponting CP, Fawkes A, Tenesa A, Caulfield M, Scott R, Rowan K, Murphy L, Openshaw PJM, Semple MG, Law A, Vitart V, Wilson JF, Baillie JK. Pairo-Castineira E, et al. Among authors: clohisey s. Nature. 2021 Mar;591(7848):92-98. doi: 10.1038/s41586-020-03065-y. Epub 2020 Dec 11. Nature. 2021. PMID: 33307546
80 results