Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

128 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment: recommendations from a joint EPAA--EURL ECVAM ADME workshop.
Bessems JG, Loizou G, Krishnan K, Clewell HJ 3rd, Bernasconi C, Bois F, Coecke S, Collnot EM, Diembeck W, Farcal LR, Geraets L, Gundert-Remy U, Kramer N, Küsters G, Leite SB, Pelkonen OR, Schröder K, Testai E, Wilk-Zasadna I, Zaldívar-Comenges JM. Bessems JG, et al. Among authors: coecke s. Regul Toxicol Pharmacol. 2014 Feb;68(1):119-39. doi: 10.1016/j.yrtph.2013.11.008. Epub 2013 Nov 26. Regul Toxicol Pharmacol. 2014. PMID: 24287156
Cytochrome P450 Induction and Xeno-Sensing Receptors Pregnane X Receptor, Constitutive Androstane Receptor, Aryl Hydrocarbon Receptor and Peroxisome Proliferator-Activated Receptor α at the Crossroads of Toxicokinetics and Toxicodynamics.
Hakkola J, Bernasconi C, Coecke S, Richert L, Andersson TB, Pelkonen O. Hakkola J, et al. Among authors: coecke s. Basic Clin Pharmacol Toxicol. 2018 Sep;123 Suppl 5:42-50. doi: 10.1111/bcpt.13004. Epub 2018 Apr 29. Basic Clin Pharmacol Toxicol. 2018. PMID: 29527807 Free article. Review.
Validation of in vitro methods for human cytochrome P450 enzyme induction: Outcome of a multi-laboratory study.
Bernasconi C, Pelkonen O, Andersson TB, Strickland J, Wilk-Zasadna I, Asturiol D, Cole T, Liska R, Worth A, Müller-Vieira U, Richert L, Chesne C, Coecke S. Bernasconi C, et al. Among authors: coecke s. Toxicol In Vitro. 2019 Oct;60:212-228. doi: 10.1016/j.tiv.2019.05.019. Epub 2019 May 31. Toxicol In Vitro. 2019. PMID: 31158489 Free PMC article.
Establishing a systematic framework to characterise in vitro methods for human hepatic metabolic clearance.
Gouliarmou V, Lostia AM, Coecke S, Bernasconi C, Bessems J, Dorne JL, Ferguson S, Testai E, Remy UG, Brian Houston J, Monshouwer M, Nong A, Pelkonen O, Morath S, Wetmore BA, Worth A, Zanelli U, Zorzoli MC, Whelan M. Gouliarmou V, et al. Among authors: coecke s. Toxicol In Vitro. 2018 Dec;53:233-244. doi: 10.1016/j.tiv.2018.08.004. Epub 2018 Aug 9. Toxicol In Vitro. 2018. PMID: 30099088 Free PMC article.
New approach methodologies (NAMs) for human-relevant biokinetics predictions. Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment.
Punt A, Bouwmeester H, Blaauboer BJ, Coecke S, Hakkert B, Hendriks DFG, Jennings P, Kramer NI, Neuhoff S, Masereeuw R, Paini A, Peijnenburg AACM, Rooseboom M, Shuler ML, Sorrell I, Spee B, Strikwold M, Van der Meer AD, Van der Zande M, Vinken M, Yang H, Bos PMJ, Heringa MB. Punt A, et al. Among authors: coecke s. ALTEX. 2020;37(4):607-622. doi: 10.14573/altex.2003242. Epub 2020 Jun 8. ALTEX. 2020. PMID: 32521035 Free article.
Guidance document on Good Cell and Tissue Culture Practice 2.0 (GCCP 2.0).
Pamies D, Leist M, Coecke S, Bowe G, Allen DG, Gstraunthaler G, Bal-Price A, Pistollato F, de Vries RBM, Hogberg HT, Hartung T, Stacey G. Pamies D, et al. Among authors: coecke s. ALTEX. 2022;39:30-70. doi: 10.14573/altex.2111011. Epub 2021 Dec 9. ALTEX. 2022. PMID: 34882777 Free article.
128 results