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NKG2D-mediated detection of metabolically stressed hepatocytes by innate-like T cells is essential for initiation of NASH and fibrosis.
Sci Immunol. 2023 Sep 29;8(87):eadd1599. doi: 10.1126/sciimmunol.add1599. Epub 2023 Sep 29.
Sci Immunol. 2023.
PMID: 37774007
Free PMC article.
IL-23 stabilizes an effector Treg cell program in the tumor microenvironment.
Wertheimer T, Zwicky P, Rindlisbacher L, Sparano C, Vermeer M, de Melo BMS, Haftmann C, Rückert T, Sethi A, Schärli S, Huber A, Ingelfinger F, Xu C, Kim D, Häne P, Fonseca da Silva A, Muschaweckh A, Nunez N, Krishnarajah S, Köhler N, Zeiser R, Oukka M, Korn T, Tugues S, Becher B.
Wertheimer T, et al. Among authors: sparano c.
Nat Immunol. 2024 Mar;25(3):512-524. doi: 10.1038/s41590-024-01755-7. Epub 2024 Feb 14.
Nat Immunol. 2024.
PMID: 38356059
Free PMC article.
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Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity.
Schadt L, Sparano C, Schweiger NA, Silina K, Cecconi V, Lucchiari G, Yagita H, Guggisberg E, Saba S, Nascakova Z, Barchet W, van den Broek M.
Schadt L, et al. Among authors: sparano c.
Cell Rep. 2019 Oct 29;29(5):1236-1248.e7. doi: 10.1016/j.celrep.2019.09.065.
Cell Rep. 2019.
PMID: 31665636
Free article.
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Embryonic and neonatal waves generate distinct populations of hepatic ILC1s.
Sparano C, Solís-Sayago D, Vijaykumar A, Rickenbach C, Vermeer M, Ingelfinger F, Litscher G, Fonseca A, Mussak C, Mayoux M, Friedrich C, Nombela-Arrieta C, Gasteiger G, Becher B, Tugues S.
Sparano C, et al.
Sci Immunol. 2022 Sep 2;7(75):eabo6641. doi: 10.1126/sciimmunol.abo6641. Epub 2022 Sep 2.
Sci Immunol. 2022.
PMID: 36054340
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Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice.
Krishnarajah S, Ingelfinger F, Friebel E, Cansever D, Amorim A, Andreadou M, Bamert D, Litscher G, Lutz M, Mayoux M, Mundt S, Ridder F, Sparano C, Stifter SA, Ulutekin C, Unger S, Vermeer M, Zwicky P, Greter M, Tugues S, De Feo D, Becher B.
Krishnarajah S, et al. Among authors: sparano c.
Nat Aging. 2022 Jan;2(1):74-89. doi: 10.1038/s43587-021-00148-x. Epub 2021 Dec 16.
Nat Aging. 2022.
PMID: 37118354
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Azathioprine therapy induces selective NK cell depletion and IFN-γ deficiency predisposing to herpesvirus reactivation.
Ingelfinger F, Sparano C, Bamert D, Reyes-Leiva D, Sethi A, Rindlisbacher L, Zwicky P, Kreutmair S, Widmer CC, Mundt S, Cortés-Vicente E, Tugues S, Becher B, Schreiner B.
Ingelfinger F, et al. Among authors: sparano c.
J Allergy Clin Immunol. 2023 Jan;151(1):280-286.e2. doi: 10.1016/j.jaci.2022.09.010. Epub 2022 Sep 16.
J Allergy Clin Immunol. 2023.
PMID: 36122787
Free article.
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