Connell JW - Search Results

1

The AAA ATPase spastin links microtubule severing to membrane modelling.

Lumb JH, Connell JW, Allison R, Reid E. Lumb JH, et al. Among authors: connell jw. Biochim Biophys Acta. 2012 Jan;1823(1):192-7. doi: 10.1016/j.bbamcr.2011.08.010. Epub 2011 Aug 25. Biochim Biophys Acta. 2012. PMID: 21888932 Free article. Review.

2

Spastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretion.

Connell JW, Lindon C, Luzio JP, Reid E. Connell JW, et al. Traffic. 2009 Jan;10(1):42-56. doi: 10.1111/j.1600-0854.2008.00847.x. Epub 2008 Oct 29. Traffic. 2009. PMID: 19000169 Free PMC article.

3

An ESCRT-spastin interaction promotes fission of recycling tubules from the endosome.

Allison R, Lumb JH, Fassier C, Connell JW, Ten Martin D, Seaman MN, Hazan J, Reid E. Allison R, et al. Among authors: connell jw. J Cell Biol. 2013 Aug 5;202(3):527-43. doi: 10.1083/jcb.201211045. Epub 2013 Jul 29. J Cell Biol. 2013. PMID: 23897888 Free PMC article.

4

Quantitative Gait Analysis Using a Motorized Treadmill System Sensitively Detects Motor Abnormalities in Mice Expressing ATPase Defective Spastin.

Connell JW, Allison R, Reid E. Connell JW, et al. PLoS One. 2016 Mar 28;11(3):e0152413. doi: 10.1371/journal.pone.0152413. eCollection 2016. PLoS One. 2016. PMID: 27019090 Free PMC article.

5

Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia.

Allison R, Edgar JR, Pearson G, Rizo T, Newton T, Günther S, Berner F, Hague J, Connell JW, Winkler J, Lippincott-Schwartz J, Beetz C, Winner B, Reid E. Allison R, et al. Among authors: connell jw. J Cell Biol. 2017 May 1;216(5):1337-1355. doi: 10.1083/jcb.201609033. Epub 2017 Apr 7. J Cell Biol. 2017. PMID: 28389476 Free PMC article.

6

ESCRT-III-associated proteins and spastin inhibit protrudin-dependent polarised membrane traffic.

Connell JW, Allison RJ, Rodger CE, Pearson G, Zlamalova E, Reid E. Connell JW, et al. Cell Mol Life Sci. 2020 Jul;77(13):2641-2658. doi: 10.1007/s00018-019-03313-z. Epub 2019 Oct 5. Cell Mol Life Sci. 2020. PMID: 31587092 Free PMC article.

7

The hereditary spastic paraplegia protein spastin interacts with the ESCRT-III complex-associated endosomal protein CHMP1B.

Reid E, Connell J, Edwards TL, Duley S, Brown SE, Sanderson CM. Reid E, et al. Hum Mol Genet. 2005 Jan 1;14(1):19-38. doi: 10.1093/hmg/ddi003. Epub 2004 Nov 10. Hum Mol Genet. 2005. PMID: 15537668

8

Spastin and atlastin, two proteins mutated in autosomal-dominant hereditary spastic paraplegia, are binding partners.

Sanderson CM, Connell JW, Edwards TL, Bright NA, Duley S, Thompson A, Luzio JP, Reid E. Sanderson CM, et al. Among authors: connell jw. Hum Mol Genet. 2006 Jan 15;15(2):307-18. doi: 10.1093/hmg/ddi447. Epub 2005 Dec 8. Hum Mol Genet. 2006. PMID: 16339213 Free PMC article.

9

The hereditary spastic paraplegia proteins NIPA1, spastin and spartin are inhibitors of mammalian BMP signalling.

Tsang HT, Edwards TL, Wang X, Connell JW, Davies RJ, Durrington HJ, O'Kane CJ, Luzio JP, Reid E. Tsang HT, et al. Among authors: connell jw. Hum Mol Genet. 2009 Oct 15;18(20):3805-21. doi: 10.1093/hmg/ddp324. Epub 2009 Jul 20. Hum Mol Genet. 2009. PMID: 19620182 Free PMC article.

10

Mutations in the ER-shaping protein reticulon 2 cause the axon-degenerative disorder hereditary spastic paraplegia type 12.

Montenegro G, Rebelo AP, Connell J, Allison R, Babalini C, D'Aloia M, Montieri P, Schüle R, Ishiura H, Price J, Strickland A, Gonzalez MA, Baumbach-Reardon L, Deconinck T, Huang J, Bernardi G, Vance JM, Rogers MT, Tsuji S, De Jonghe P, Pericak-Vance MA, Schöls L, Orlacchio A, Reid E, Züchner S. Montenegro G, et al. J Clin Invest. 2012 Feb;122(2):538-44. doi: 10.1172/JCI60560. Epub 2012 Jan 9. J Clin Invest. 2012. PMID: 22232211 Free PMC article.

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