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Year | Number of Results |
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2021 | 4 |
2022 | 1 |
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Page 1
Targeted protein degradation via intramolecular bivalent glues.
Nature. 2024 Mar;627(8002):204-211. doi: 10.1038/s41586-024-07089-6. Epub 2024 Feb 21.
Nature. 2024.
PMID: 38383787
Free PMC article.
Targeting epigenetic modulators using PROTAC degraders: Current status and future perspective.
Webb T, Craigon C, Ciulli A.
Webb T, et al. Among authors: craigon c.
Bioorg Med Chem Lett. 2022 May 1;63:128653. doi: 10.1016/j.bmcl.2022.128653. Epub 2022 Mar 4.
Bioorg Med Chem Lett. 2022.
PMID: 35257896
Free article.
Review.
Item in Clipboard
Mechanistic and Structural Features of PROTAC Ternary Complexes.
Casement R, Bond A, Craigon C, Ciulli A.
Casement R, et al. Among authors: craigon c.
Methods Mol Biol. 2021;2365:79-113. doi: 10.1007/978-1-0716-1665-9_5.
Methods Mol Biol. 2021.
PMID: 34432240
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Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity.
Imaide S, Riching KM, Makukhin N, Vetma V, Whitworth C, Hughes SJ, Trainor N, Mahan SD, Murphy N, Cowan AD, Chan KH, Craigon C, Testa A, Maniaci C, Urh M, Daniels DL, Ciulli A.
Imaide S, et al. Among authors: craigon c.
Nat Chem Biol. 2021 Nov;17(11):1157-1167. doi: 10.1038/s41589-021-00878-4. Epub 2021 Oct 21.
Nat Chem Biol. 2021.
PMID: 34675414
Free PMC article.
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Amide-to-Ester Substitution as a Strategy for Optimizing PROTAC Permeability and Cellular Activity.
Klein VG, Bond AG, Craigon C, Lokey RS, Ciulli A.
Klein VG, et al. Among authors: craigon c.
J Med Chem. 2021 Dec 23;64(24):18082-18101. doi: 10.1021/acs.jmedchem.1c01496. Epub 2021 Dec 9.
J Med Chem. 2021.
PMID: 34881891
Free PMC article.
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Development of BromoTag: A "Bump-and-Hole"-PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins.
Bond AG, Craigon C, Chan KH, Testa A, Karapetsas A, Fasimoye R, Macartney T, Blow JJ, Alessi DR, Ciulli A.
Bond AG, et al. Among authors: craigon c.
J Med Chem. 2021 Oct 28;64(20):15477-15502. doi: 10.1021/acs.jmedchem.1c01532. Epub 2021 Oct 15.
J Med Chem. 2021.
PMID: 34652918
Free PMC article.
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