Conrad J - Search Results

1

Photoredox Cyanomethylation of Indoles: Catalyst Modification and Mechanism.

O'Brien CJ, Droege DG, Jiu AY, Gandhi SS, Paras NA, Olson SH, Conrad J. O'Brien CJ, et al. Among authors: conrad j. J Org Chem. 2018 Aug 17;83(16):8926-8935. doi: 10.1021/acs.joc.8b01146. Epub 2018 Jul 6. J Org Chem. 2018. PMID: 29940725 Free PMC article.

2

Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity.

Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, Inoue M, Olson SH, Prusiner SB, Conrad J, Paras NA. Grandjean JM, et al. Among authors: conrad j. ACS Med Chem Lett. 2020 Jan 30;11(2):127-132. doi: 10.1021/acsmedchemlett.9b00480. eCollection 2020 Feb 13. ACS Med Chem Lett. 2020. PMID: 32071678 Free PMC article.

3

Selectivity in the Addition of Electron Deficient Radicals to the C2 Position of Indoles.

Li Y, Vaz RJ, Olson SH, Munson M, Paras NA, Conrad J. Li Y, et al. Among authors: conrad j. European J Org Chem. 2020 Sep 30;2020(36):5828-5832. doi: 10.1002/ejoc.201901784. Epub 2020 Aug 18. European J Org Chem. 2020. PMID: 33692651 Free PMC article.

4

Silver Benzoate Facilitates the Copper-Catalyzed C-N Coupling of Iodoazoles with Aromatic Nitrogen Heterocycles.

Lozano C, Ramirez C, Sin N, Viart HM, Prusiner SB, Paras NA, Conrad J. Lozano C, et al. Among authors: conrad j. ACS Omega. 2021 Mar 31;6(14):9804-9812. doi: 10.1021/acsomega.1c00458. eCollection 2021 Apr 13. ACS Omega. 2021. PMID: 33869960 Free PMC article.

5

Water-Soluble Iridium Photoredox Catalyst for the Trifluoromethylation of Biomolecule Substrates in Phosphate Buffered Saline Solvent.

Nguyen TH, O'Brien CJ, Tran MLN, Olson SH, Settineri NS, Prusiner SB, Paras NA, Conrad J. Nguyen TH, et al. Among authors: conrad j. Org Lett. 2021 May 21;23(10):3823-3827. doi: 10.1021/acs.orglett.1c00871. Epub 2021 Apr 30. Org Lett. 2021. PMID: 33929208

6

Model of P-Glycoprotein Ligand Binding and Validation with Efflux Substrate Matched Pairs.

Conrad J, Paras NA, Vaz RJ. Conrad J, et al. J Med Chem. 2024 Apr 11;67(7):5854-5865. doi: 10.1021/acs.jmedchem.4c00139. Epub 2024 Mar 27. J Med Chem. 2024. PMID: 38544305 Free PMC article.

7

Enantioselective α-Alkylation of Aldehydes by Photoredox Organocatalysis: Rapid Access to Pharmacophore Fragments from β-Cyanoaldehydes.

Welin ER, Warkentin AA, Conrad JC, MacMillan DW. Welin ER, et al. Angew Chem Int Ed Engl. 2015 Aug 10;54(33):9668-72. doi: 10.1002/anie.201503789. Epub 2015 Jun 30. Angew Chem Int Ed Engl. 2015. PMID: 26130043 Free PMC article.

8

Enantioselective alpha-arylation of aldehydes via organo-SOMO catalysis. An ortho-selective arylation reaction based on an open-shell pathway.

Conrad JC, Kong J, Laforteza BN, MacMillan DW. Conrad JC, et al. J Am Chem Soc. 2009 Aug 26;131(33):11640-1. doi: 10.1021/ja9026902. J Am Chem Soc. 2009. PMID: 19639997 Free PMC article.

9

Mechanistic complexity in organo-SOMO activation.

Devery JJ 3rd, Conrad JC, MacMillan DW, Flowers RA 2nd. Devery JJ 3rd, et al. Among authors: conrad jc. Angew Chem Int Ed Engl. 2010 Aug 16;49(35):6106-10. doi: 10.1002/anie.201001673. Angew Chem Int Ed Engl. 2010. PMID: 20632343 Free PMC article. No abstract available.

10

Enantioselective organocatalytic α-fluorination of cyclic ketones.

Kwiatkowski P, Beeson TD, Conrad JC, MacMillan DW. Kwiatkowski P, et al. J Am Chem Soc. 2011 Feb 16;133(6):1738-41. doi: 10.1021/ja111163u. Epub 2011 Jan 19. J Am Chem Soc. 2011. PMID: 21247133 Free PMC article.

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