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PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing.
Danileviciute E, Zeng N, Capelle CM, Paczia N, Gillespie MA, Kurniawan H, Benzarti M, Merz MP, Coowar D, Fritah S, Vogt Weisenhorn DM, Gomez Giro G, Grusdat M, Baron A, Guerin C, Franchina DG, Léonard C, Domingues O, Delhalle S, Wurst W, Turner JD, Schwamborn JC, Meiser J, Krüger R, Ranish J, Brenner D, Linster CL, Balling R, Ollert M, Hefeng FQ. Danileviciute E, et al. Among authors: coowar d. Nat Metab. 2022 May;4(5):589-607. doi: 10.1038/s42255-022-00576-y. Epub 2022 May 26. Nat Metab. 2022. PMID: 35618940
DJ-1 depletion prevents immunoaging in T-cell compartments.
Zeng N, Capelle CM, Baron A, Kobayashi T, Cire S, Tslaf V, Leonard C, Coowar D, Koseki H, Westendorf AM, Buer J, Brenner D, Krüger R, Balling R, Ollert M, Hefeng FQ. Zeng N, et al. Among authors: coowar d. EMBO Rep. 2022 Feb 3;23(3):e53302. doi: 10.15252/embr.202153302. Epub 2022 Jan 17. EMBO Rep. 2022. PMID: 35037711 Free PMC article.
Neurodegeneration and neuroinflammation are linked, but independent of alpha-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease.
Garcia P, Jürgens-Wemheuer W, Uriarte Huarte O, Michelucci A, Masuch A, Brioschi S, Weihofen A, Koncina E, Coowar D, Heurtaux T, Glaab E, Balling R, Sousa C, Kaoma T, Nicot N, Pfander T, Schulz-Schaeffer W, Allouche A, Fischer N, Biber K, Kleine-Borgmann F, Mittelbronn M, Ostaszewski M, Schmit KJ, Buttini M. Garcia P, et al. Among authors: coowar d. Glia. 2022 May;70(5):935-960. doi: 10.1002/glia.24149. Epub 2022 Jan 29. Glia. 2022. PMID: 35092321 Free PMC article.
Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures.
Sousa C, Golebiewska A, Poovathingal SK, Kaoma T, Pires-Afonso Y, Martina S, Coowar D, Azuaje F, Skupin A, Balling R, Biber K, Niclou SP, Michelucci A. Sousa C, et al. Among authors: coowar d. EMBO Rep. 2018 Nov;19(11):e46171. doi: 10.15252/embr.201846171. Epub 2018 Sep 11. EMBO Rep. 2018. PMID: 30206190 Free PMC article.
Elucidating tumour-associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency.
Pires-Afonso Y, Muller A, Grzyb K, Oudin A, Yabo YA, Sousa C, Scafidi A, Poli A, Cosma A, Halder R, Coowar D, Golebiewska A, Skupin A, Niclou SP, Michelucci A. Pires-Afonso Y, et al. Among authors: coowar d. Mol Oncol. 2022 Sep;16(17):3167-3191. doi: 10.1002/1878-0261.13287. Epub 2022 Aug 15. Mol Oncol. 2022. PMID: 35838338 Free PMC article.
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