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Tankyrase inhibition promotes a stable human naïve pluripotent state with improved functionality.
Zimmerlin L, Park TS, Huo JS, Verma K, Pather SR, Talbot CC Jr, Agarwal J, Steppan D, Zhang YW, Considine M, Guo H, Zhong X, Gutierrez C, Cope L, Canto-Soler MV, Friedman AD, Baylin SB, Zambidis ET. Zimmerlin L, et al. Among authors: cope l. Development. 2016 Dec 1;143(23):4368-4380. doi: 10.1242/dev.138982. Epub 2016 Sep 22. Development. 2016. PMID: 27660325 Free PMC article.
Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.
Schuebel KE, Chen W, Cope L, Glöckner SC, Suzuki H, Yi JM, Chan TA, Van Neste L, Van Criekinge W, van den Bosch S, van Engeland M, Ting AH, Jair K, Yu W, Toyota M, Imai K, Ahuja N, Herman JG, Baylin SB. Schuebel KE, et al. Among authors: cope l. PLoS Genet. 2007 Sep;3(9):1709-23. doi: 10.1371/journal.pgen.0030157. Epub 2007 Jul 31. PLoS Genet. 2007. PMID: 17892325 Free PMC article.
Transcriptional regulation of Wnt inhibitory factor-1 by Miz-1/c-Myc.
Licchesi JD, Van Neste L, Tiwari VK, Cope L, Lin X, Baylin SB, Herman JG. Licchesi JD, et al. Among authors: cope l. Oncogene. 2010 Nov 4;29(44):5923-34. doi: 10.1038/onc.2010.322. Epub 2010 Aug 9. Oncogene. 2010. PMID: 20697356 Free PMC article.
Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells.
Ohm JE, Mali P, Van Neste L, Berman DM, Liang L, Pandiyan K, Briggs KJ, Zhang W, Argani P, Simons B, Yu W, Matsui W, Van Criekinge W, Rassool FV, Zambidis E, Schuebel KE, Cope L, Yen J, Mohammad HP, Cheng L, Baylin SB. Ohm JE, et al. Among authors: cope l. Cancer Res. 2010 Oct 1;70(19):7662-73. doi: 10.1158/0008-5472.CAN-10-1361. Epub 2010 Sep 14. Cancer Res. 2010. PMID: 20841480 Free PMC article.
Biomarkers for detection and prognosis of breast cancer identified by a functional hypermethylome screen.
Jeschke J, Van Neste L, Glöckner SC, Dhir M, Calmon MF, Deregowski V, Van Criekinge W, Vlassenbroeck I, Koch A, Chan TA, Cope L, Hooker CM, Schuebel KE, Gabrielson E, Winterpacht A, Baylin SB, Herman JG, Ahuja N. Jeschke J, et al. Among authors: cope l. Epigenetics. 2012 Jul;7(7):701-9. doi: 10.4161/epi.20445. Epub 2012 Jul 1. Epigenetics. 2012. PMID: 22647880
368 results