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53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.
Ghezraoui H, Oliveira C, Becker JR, Bilham K, Moralli D, Anzilotti C, Fischer R, Deobagkar-Lele M, Sanchiz-Calvo M, Fueyo-Marcos E, Bonham S, Kessler BM, Rottenberg S, Cornall RJ, Green CM, Chapman JR. Ghezraoui H, et al. Among authors: cornall rj. Nature. 2018 Aug;560(7716):122-127. doi: 10.1038/s41586-018-0362-1. Epub 2018 Jul 25. Nature. 2018. PMID: 30046110 Free PMC article.
DNA repair is limiting for haematopoietic stem cells during ageing.
Nijnik A, Woodbine L, Marchetti C, Dawson S, Lambe T, Liu C, Rodrigues NP, Crockford TL, Cabuy E, Vindigni A, Enver T, Bell JI, Slijepcevic P, Goodnow CC, Jeggo PA, Cornall RJ. Nijnik A, et al. Among authors: cornall rj. Nature. 2007 Jun 7;447(7145):686-90. doi: 10.1038/nature05875. Nature. 2007. PMID: 17554302
Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity.
Siggs OM, Stockenhuber A, Deobagkar-Lele M, Bull KR, Crockford TL, Kingston BL, Crawford G, Anzilotti C, Steeples V, Ghaffari S, Czibik G, Bellahcene M, Watkins H, Ashrafian H, Davies B, Woods A, Carling D, Yavari A, Beutler B, Cornall RJ. Siggs OM, et al. Among authors: cornall rj. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3706-15. doi: 10.1073/pnas.1607592113. Epub 2016 Jun 14. Proc Natl Acad Sci U S A. 2016. PMID: 27303042 Free PMC article.
Themis2 lowers the threshold for B cell activation during positive selection.
Cheng D, Deobagkar-Lele M, Zvezdova E, Choi S, Uehara S, Baup D, Bennett SC, Bull KR, Crockford TL, Ferry H, Warzecha C, Marcellin M, de Peredo AG, Lesourne R, Anzilotti C, Love PE, Cornall RJ. Cheng D, et al. Among authors: cornall rj. Nat Immunol. 2017 Feb;18(2):205-213. doi: 10.1038/ni.3642. Epub 2016 Dec 19. Nat Immunol. 2017. PMID: 27992403
Themis2: setting the threshold for B-cell selection.
Deobagkar-Lele M, Anzilotti C, Cornall RJ. Deobagkar-Lele M, et al. Among authors: cornall rj. Cell Mol Immunol. 2017 Aug;14(8):643-645. doi: 10.1038/cmi.2017.27. Epub 2017 Jun 19. Cell Mol Immunol. 2017. PMID: 28626236 Free PMC article. No abstract available.
Capturing resting T cells: the perils of PLL.
Santos AM, Ponjavic A, Fritzsche M, Fernandes RA, de la Serna JB, Wilcock MJ, Schneider F, Urbančič I, McColl J, Anzilotti C, Ganzinger KA, Aßmann M, Depoil D, Cornall RJ, Dustin ML, Klenerman D, Davis SJ, Eggeling C, Lee SF. Santos AM, et al. Among authors: cornall rj. Nat Immunol. 2018 Mar;19(3):203-205. doi: 10.1038/s41590-018-0048-8. Epub 2018 Feb 23. Nat Immunol. 2018. PMID: 29476188 Free PMC article. No abstract available.
Immune Checkpoints as Therapeutic Targets in Autoimmunity.
Paluch C, Santos AM, Anzilotti C, Cornall RJ, Davis SJ. Paluch C, et al. Among authors: cornall rj. Front Immunol. 2018 Oct 8;9:2306. doi: 10.3389/fimmu.2018.02306. eCollection 2018. Front Immunol. 2018. PMID: 30349540 Free PMC article. Review.
An essential role for the Zn2+ transporter ZIP7 in B cell development.
Anzilotti C, Swan DJ, Boisson B, Deobagkar-Lele M, Oliveira C, Chabosseau P, Engelhardt KR, Xu X, Chen R, Alvarez L, Berlinguer-Palmini R, Bull KR, Cawthorne E, Cribbs AP, Crockford TL, Dang TS, Fearn A, Fenech EJ, de Jong SJ, Lagerholm BC, Ma CS, Sims D, van den Berg B, Xu Y, Cant AJ, Kleiner G, Leahy TR, de la Morena MT, Puck JM, Shapiro RS, van der Burg M, Chapman JR, Christianson JC, Davies B, McGrath JA, Przyborski S, Santibanez Koref M, Tangye SG, Werner A, Rutter GA, Padilla-Parra S, Casanova JL, Cornall RJ, Conley ME, Hambleton S. Anzilotti C, et al. Among authors: cornall rj. Nat Immunol. 2019 Mar;20(3):350-361. doi: 10.1038/s41590-018-0295-8. Epub 2019 Feb 4. Nat Immunol. 2019. PMID: 30718914 Free PMC article.
An ontogenetic switch drives the positive and negative selection of B cells.
Xu X, Deobagkar-Lele M, Bull KR, Crockford TL, Mead AJ, Cribbs AP, Sims D, Anzilotti C, Cornall RJ. Xu X, et al. Among authors: cornall rj. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3718-3727. doi: 10.1073/pnas.1915247117. Epub 2020 Feb 4. Proc Natl Acad Sci U S A. 2020. PMID: 32019891 Free PMC article.
Dynamic regulation of hypoxia-inducible factor-1α activity is essential for normal B cell development.
Burrows N, Bashford-Rogers RJM, Bhute VJ, Peñalver A, Ferdinand JR, Stewart BJ, Smith JEG, Deobagkar-Lele M, Giudice G, Connor TM, Inaba A, Bergamaschi L, Smith S, Tran MGB, Petsalaki E, Lyons PA, Espeli M, Huntly BJP, Smith KGC, Cornall RJ, Clatworthy MR, Maxwell PH. Burrows N, et al. Among authors: cornall rj. Nat Immunol. 2020 Nov;21(11):1408-1420. doi: 10.1038/s41590-020-0772-8. Epub 2020 Aug 31. Nat Immunol. 2020. PMID: 32868930 Free PMC article.
94 results