Cornea A - Search Results

1

Human loss-of-function gonadotropin-releasing hormone receptor mutants retain wild-type receptors in the endoplasmic reticulum: molecular basis of the dominant-negative effect.

Brothers SP, Cornea A, Janovick JA, Conn PM. Brothers SP, et al. Among authors: cornea a. Mol Endocrinol. 2004 Jul;18(7):1787-97. doi: 10.1210/me.2004-0091. Epub 2004 Apr 22. Mol Endocrinol. 2004. PMID: 15105440

2

Conserved mammalian gonadotropin-releasing hormone receptor carboxyl terminal amino acids regulate ligand binding, effector coupling and internalization.

Brothers SP, Janovick JA, Maya-Nunez G, Cornea A, Han XB, Conn PM. Brothers SP, et al. Among authors: cornea a. Mol Cell Endocrinol. 2002 Apr 25;190(1-2):19-27. doi: 10.1016/s0303-7207(02)00040-0. Mol Cell Endocrinol. 2002. PMID: 11997175

3

Measurement of changes in fluorescence resonance energy transfer between gonadotropin-releasing hormone receptors in response to agonists.

Cornea A, Conn PM. Cornea A, et al. Methods. 2002 Aug;27(4):333-9. doi: 10.1016/s1046-2023(02)00091-9. Methods. 2002. PMID: 12217649

4

Refolding of misfolded mutant GPCR: post-translational pharmacoperone action in vitro.

Janovick JA, Brothers SP, Cornea A, Bush E, Goulet MT, Ashton WT, Sauer DR, Haviv F, Greer J, Conn PM. Janovick JA, et al. Among authors: cornea a. Mol Cell Endocrinol. 2007 Jun 30;272(1-2):77-85. doi: 10.1016/j.mce.2007.04.012. Epub 2007 May 3. Mol Cell Endocrinol. 2007. PMID: 17555869 Free PMC article.

5

Molecular mechanism of action of pharmacoperone rescue of misrouted GPCR mutants: the GnRH receptor.

Janovick JA, Patny A, Mosley R, Goulet MT, Altman MD, Rush TS 3rd, Cornea A, Conn PM. Janovick JA, et al. Among authors: cornea a. Mol Endocrinol. 2009 Feb;23(2):157-68. doi: 10.1210/me.2008-0384. Epub 2008 Dec 18. Mol Endocrinol. 2009. PMID: 19095769 Free PMC article.

6

Rescue of misrouted GnRHR mutants reveals its constitutive activity.

Janovick JA, Pogozheva ID, Mosberg HI, Cornea A, Conn PM. Janovick JA, et al. Among authors: cornea a. Mol Endocrinol. 2012 Jul;26(7):1179-88. doi: 10.1210/me.2012-1089. Epub 2012 May 17. Mol Endocrinol. 2012. PMID: 22595961 Free PMC article.

7

Restoration of testis function in hypogonadotropic hypogonadal mice harboring a misfolded GnRHR mutant by pharmacoperone drug therapy.

Janovick JA, Stewart MD, Jacob D, Martin LD, Deng JM, Stewart CA, Wang Y, Cornea A, Chavali L, Lopez S, Mitalipov S, Kang E, Lee HS, Manna PR, Stocco DM, Behringer RR, Conn PM. Janovick JA, et al. Among authors: cornea a. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21030-5. doi: 10.1073/pnas.1315194110. Epub 2013 Dec 9. Proc Natl Acad Sci U S A. 2013. PMID: 24324164 Free PMC article.

8

Redistribution of G(q/11)alpha in the pituitary gonadotrope in response to a gonadotropin-releasing hormone agonist.

Cornea A, Janovick JA, Stanislaus D, Conn PM. Cornea A, et al. Endocrinology. 1998 Jan;139(1):397-402. doi: 10.1210/endo.139.1.5687. Endocrinology. 1998. PMID: 9421439

9

Visualization of unoccupied and occupied gonadotropin-releasing hormone receptors in living cells.

Lin X, Cornea A, Janovick JA, Conn PM. Lin X, et al. Among authors: cornea a. Mol Cell Endocrinol. 1998 Nov 25;146(1-2):27-37. doi: 10.1016/s0303-7207(98)00204-4. Mol Cell Endocrinol. 1998. PMID: 10022760

10

Simultaneous and independent visualization of the gonadotropin-releasing hormone receptor and its ligand: evidence for independent processing and recycling in living cells.

Cornea A, Janovick JA, Lin X, Conn PM. Cornea A, et al. Endocrinology. 1999 Sep;140(9):4272-80. doi: 10.1210/endo.140.9.7049. Endocrinology. 1999. PMID: 10465301

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