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MCL1 inhibitors S63845/MIK665 plus Navitoclax synergistically kill difficult-to-treat melanoma cells.
Mukherjee N, Skees J, Todd KJ, West DA, Lambert KA, Robinson WA, Amato CM, Couts KL, Van Gulick R, MacBeth M, Nassar K, Tan AC, Zhai Z, Fujita M, Bagby SM, Dart CR, Lambert JR, Norris DA, Shellman YG. Mukherjee N, et al. Among authors: couts kl. Cell Death Dis. 2020 Jun 8;11(6):443. doi: 10.1038/s41419-020-2646-2. Cell Death Dis. 2020. PMID: 32513939 Free PMC article.
Understanding melanoma stem cells.
Nguyen N, Couts KL, Luo Y, Fujita M. Nguyen N, et al. Among authors: couts kl. Melanoma Manag. 2015;2(2):179-188. doi: 10.2217/mmt.15.4. Melanoma Manag. 2015. PMID: 26594315 Free PMC article.
Kinase gene fusions in defined subsets of melanoma.
Turner J, Couts K, Sheren J, Saichaemchan S, Ariyawutyakorn W, Avolio I, Cabral E, Glogowska M, Amato C, Robinson S, Hintzsche J, Applegate A, Seelenfreund E, Gonzalez R, Wells K, Bagby S, Tentler J, Tan AC, Wisell J, Varella-Garcia M, Robinson W. Turner J, et al. Pigment Cell Melanoma Res. 2017 Jan;30(1):53-62. doi: 10.1111/pcmr.12560. Pigment Cell Melanoma Res. 2017. PMID: 27864876 Free PMC article.
Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma.
Hintzsche JD, Gorden NT, Amato CM, Kim J, Wuensch KE, Robinson SE, Applegate AJ, Couts KL, Medina TM, Wells KR, Wisell JA, McCarter MD, Box NF, Shellman YG, Gonzalez RC, Lewis KD, Tentler JJ, Tan AC, Robinson WA. Hintzsche JD, et al. Among authors: couts kl. Melanoma Res. 2017 Jun;27(3):189-199. doi: 10.1097/CMR.0000000000000345. Melanoma Res. 2017. PMID: 28296713 Free PMC article.
ALK Inhibitor Response in Melanomas Expressing EML4-ALK Fusions and Alternate ALK Isoforms.
Couts KL, Bemis J, Turner JA, Bagby SM, Murphy D, Christiansen J, Hintzsche JD, Le A, Pitts TM, Wells K, Applegate A, Amato C, Multani P, Chow-Maneval E, Tentler JJ, Shellman YG, Rioth MJ, Tan AC, Gonzalez R, Medina T, Doebele RC, Robinson WA. Couts KL, et al. Mol Cancer Ther. 2018 Jan;17(1):222-231. doi: 10.1158/1535-7163.MCT-17-0472. Epub 2017 Oct 20. Mol Cancer Ther. 2018. PMID: 29054983 Free PMC article.
BH3 mimetics induce apoptosis independent of DRP-1 in melanoma.
Mukherjee N, Strosnider A, Vagher B, Lambert KA, Slaven S, Robinson WA, Amato CM, Couts KL, Bemis JGT, Turner JA, Norris DA, Shellman YG. Mukherjee N, et al. Among authors: couts kl. Cell Death Dis. 2018 Sep 5;9(9):907. doi: 10.1038/s41419-018-0932-z. Cell Death Dis. 2018. PMID: 30185782 Free PMC article.
BRAF fusions identified in melanomas have variable treatment responses and phenotypes.
Turner JA, Bemis JGT, Bagby SM, Capasso A, Yacob BW, Chimed TS, Van Gulick R, Lee H, Tobin R, Tentler JJ, Pitts T, McCarter M, Robinson WA, Couts KL. Turner JA, et al. Among authors: couts kl. Oncogene. 2019 Feb;38(8):1296-1308. doi: 10.1038/s41388-018-0514-7. Epub 2018 Sep 25. Oncogene. 2019. PMID: 30254212
IL-6 and IL-8 Are Linked With Myeloid-Derived Suppressor Cell Accumulation and Correlate With Poor Clinical Outcomes in Melanoma Patients.
Tobin RP, Jordan KR, Kapoor P, Spongberg E, Davis D, Vorwald VM, Couts KL, Gao D, Smith DE, Borgers JSW, Robinson S, Amato C, Gonzalez R, Lewis KD, Robinson WA, Borges VF, McCarter MD. Tobin RP, et al. Among authors: couts kl. Front Oncol. 2019 Nov 8;9:1223. doi: 10.3389/fonc.2019.01223. eCollection 2019. Front Oncol. 2019. PMID: 31781510 Free PMC article.
Melanoma Metastases to the Adrenal Gland Are Highly Resistant to Immune Checkpoint Inhibitors.
Borgers JSW, Tobin RP, Torphy RJ, Vorwald VM, Van Gulick RJ, Amato CM, Cogswell DT, Chimed TS, Couts KL, Van Bokhoven A, Raeburn CD, Lewis KD, Wisell J, McCarter MD, Mushtaq RR, Robinson WA. Borgers JSW, et al. Among authors: couts kl. J Natl Compr Canc Netw. 2021 Aug 4:jnccn20283. doi: 10.6004/jnccn.2020.7800. Online ahead of print. J Natl Compr Canc Netw. 2021. PMID: 34348236
30 results