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Uptake of long-chain fatty acids from the bone marrow suppresses CD8+ T-cell metabolism and function in multiple myeloma.
Blood Adv. 2023 Oct 24;7(20):6035-6047. doi: 10.1182/bloodadvances.2023009890.
Blood Adv. 2023.
PMID: 37276076
Free PMC article.
Mathematical reconstruction of the metabolic network in an in-vitro multiple myeloma model.
Vera-Siguenza E, Escribano-Gonzalez C, Serrano-Gonzalo I, Eskla KL, Spill F, Tennant D.
Vera-Siguenza E, et al. Among authors: escribano gonzalez c.
PLoS Comput Biol. 2023 Sep 15;19(9):e1011374. doi: 10.1371/journal.pcbi.1011374. eCollection 2023 Sep.
PLoS Comput Biol. 2023.
PMID: 37713666
Free PMC article.
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Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions.
Westbrook RL, Bridges E, Roberts J, Escribano-Gonzalez C, Eales KL, Vettore LA, Walker PD, Vera-Siguenza E, Rana H, Cuozzo F, Eskla KL, Vellama H, Shaaban A, Nixon C, Luuk H, Lavery GG, Hodson DJ, Harris AL, Tennant DA.
Westbrook RL, et al. Among authors: escribano gonzalez c.
Cell Rep. 2022 Feb 1;38(5):110320. doi: 10.1016/j.celrep.2022.110320.
Cell Rep. 2022.
PMID: 35108535
Free PMC article.
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Succinate dehydrogenase deficiency in a chromaffin cell model retains metabolic fitness through the maintenance of mitochondrial NADH oxidoreductase function.
Kľučková K, Thakker A, Vettore L, Escribano-Gonzalez C, Hindshaw RL, Tearle JLE, Goncalves J, Kaul B, Lavery GG, Favier J, Tennant DA.
Kľučková K, et al. Among authors: escribano gonzalez c.
FASEB J. 2020 Jan;34(1):303-315. doi: 10.1096/fj.201901456R. Epub 2019 Nov 22.
FASEB J. 2020.
PMID: 31914648
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Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis.
Hollinshead KER, Munford H, Eales KL, Bardella C, Li C, Escribano-Gonzalez C, Thakker A, Nonnenmacher Y, Kluckova K, Jeeves M, Murren R, Cuozzo F, Ye D, Laurenti G, Zhu W, Hiller K, Hodson DJ, Hua W, Tomlinson IP, Ludwig C, Mao Y, Tennant DA.
Hollinshead KER, et al. Among authors: escribano gonzalez c.
Cell Rep. 2018 Mar 20;22(12):3107-3114. doi: 10.1016/j.celrep.2018.02.084.
Cell Rep. 2018.
PMID: 29562167
Free PMC article.
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