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Page 1
Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment.
Quevedo CE, Cruz-Migoni A, Bery N, Miller A, Tanaka T, Petch D, Bataille CJR, Lee LYW, Fallon PS, Tulmin H, Ehebauer MT, Fernandez-Fuentes N, Russell AJ, Carr SB, Phillips SEV, Rabbitts TH. Quevedo CE, et al. Among authors: cruz migoni a. Nat Commun. 2018 Aug 9;9(1):3169. doi: 10.1038/s41467-018-05707-2. Nat Commun. 2018. PMID: 30093669 Free PMC article.
Cloning, purification and structure determination of the HIV integrase-binding domain of lens epithelium-derived growth factor.
Hannon C, Cruz-Migoni A, Platonova O, Owen RL, Nettleship JE, Miller A, Carr SB, Harris G, Rabbitts TH, Phillips SEV. Hannon C, et al. Among authors: cruz migoni a. Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74(Pt 3):143-149. doi: 10.1107/S2053230X18001553. Epub 2018 Feb 26. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 29497017 Free PMC article.
Repeat expansions confer WRN dependence in microsatellite-unstable cancers.
van Wietmarschen N, Sridharan S, Nathan WJ, Tubbs A, Chan EM, Callen E, Wu W, Belinky F, Tripathi V, Wong N, Foster K, Noorbakhsh J, Garimella K, Cruz-Migoni A, Sommers JA, Huang Y, Borah AA, Smith JT, Kalfon J, Kesten N, Fugger K, Walker RL, Dolzhenko E, Eberle MA, Hayward BE, Usdin K, Freudenreich CH, Brosh RM Jr, West SC, McHugh PJ, Meltzer PS, Bass AJ, Nussenzweig A. van Wietmarschen N, et al. Among authors: cruz migoni a. Nature. 2020 Oct;586(7828):292-298. doi: 10.1038/s41586-020-2769-8. Epub 2020 Sep 30. Nature. 2020. PMID: 32999459 Free PMC article.
Cloning, purification and crystallographic analysis of a hypothetical protein, BPSL1549, from Burkholderia pseudomallei.
Cruz-Migoni A, Ruzheinikov SN, Sedelnikova SE, Obeng B, Chieng S, Mohamed R, Nathan S, Baker PJ, Rice DW. Cruz-Migoni A, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1623-6. doi: 10.1107/S1744309111028995. Epub 2011 Nov 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 22139182 Free PMC article.
Characterization of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification.
Baddock HT, Brolih S, Yosaatmadja Y, Ratnaweera M, Bielinski M, Swift LP, Cruz-Migoni A, Fan H, Keown JR, Walker AP, Morris GM, Grimes JM, Fodor E, Schofield CJ, Gileadi O, McHugh PJ. Baddock HT, et al. Among authors: cruz migoni a. Nucleic Acids Res. 2022 Feb 22;50(3):1484-1500. doi: 10.1093/nar/gkab1303. Nucleic Acids Res. 2022. PMID: 35037045 Free PMC article.
A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A.
Cruz-Migoni A, Hautbergue GM, Artymiuk PJ, Baker PJ, Bokori-Brown M, Chang CT, Dickman MJ, Essex-Lopresti A, Harding SV, Mahadi NM, Marshall LE, Mobbs GW, Mohamed R, Nathan S, Ngugi SA, Ong C, Ooi WF, Partridge LJ, Phillips HL, Raih MF, Ruzheinikov S, Sarkar-Tyson M, Sedelnikova SE, Smither SJ, Tan P, Titball RW, Wilson SA, Rice DW. Cruz-Migoni A, et al. Science. 2011 Nov 11;334(6057):821-4. doi: 10.1126/science.1211915. Science. 2011. PMID: 22076380 Free PMC article.