Neutral sphingomyelinase inhibitor scyphostatin prevents and ceramide mimics mechanotransduction in vascular endothelium.
Czarny M, Schnitzer JE.
Czarny M, et al.
Am J Physiol Heart Circ Physiol. 2004 Sep;287(3):H1344-52. doi: 10.1152/ajpheart.00222.2004. Epub 2004 May 13.
Am J Physiol Heart Circ Physiol. 2004.
PMID: 15142848
Free article.
Recently, we showed that neutral sphingomyelinase (N-SMase) is concentrated at the endothelial cell surface in caveolae and is activated to produce ceramide in an acute and transient manner by increase in flow rate and pressure in rat lung vasculature (Czarny M, Liu …
Recently, we showed that neutral sphingomyelinase (N-SMase) is concentrated at the endothelial cell surface in caveolae and is activated to …