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Fluorizoline Blocks the Interaction between Prohibitin-2 and γ-Glutamylcyclotransferase and Induces p21Waf1/Cip1 Expression in MCF7 Breast Cancer Cells.
Takagi H, Moyama C, Taniguchi K, Ando K, Matsuda R, Ando S, Ii H, Kageyama S, Kawauchi A, Chouha N, Désaubry L, Nakata S. Takagi H, et al. Among authors: desaubry l. Mol Pharmacol. 2022 Feb;101(2):78-86. doi: 10.1124/molpharm.121.000334. Epub 2021 Dec 3. Mol Pharmacol. 2022. PMID: 34862308 Free article.
The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells ex vivo but fails to prevent leukemia development in a murine model.
Wierz M, Pierson S, Chouha N, Désaubry L, François JH, Berchem G, Paggetti J, Moussay E. Wierz M, et al. Among authors: desaubry l. Haematologica. 2018 Apr;103(4):e154-e157. doi: 10.3324/haematol.2017.175349. Epub 2018 Jan 5. Haematologica. 2018. PMID: 29305413 Free PMC article. No abstract available.
Prohibitin (PHB) expression is associated with aggressiveness in DLBCL and flavagline-mediated inhibition of cytoplasmic PHB functions induces anti-tumor effects.
Bentayeb H, Aitamer M, Petit B, Dubanet L, Elderwish S, Désaubry L, de Gramont A, Raymond E, Olivrie A, Abraham J, Jauberteau MO, Troutaud D. Bentayeb H, et al. Among authors: desaubry l. J Exp Clin Cancer Res. 2019 Nov 4;38(1):450. doi: 10.1186/s13046-019-1440-4. J Exp Clin Cancer Res. 2019. PMID: 31684984 Free PMC article.
SFPH proteins as therapeutic targets for a myriad of diseases.
Wang D, Tabti R, Elderwish S, Djehal A, Chouha N, Pinot F, Yu P, Nebigil CG, Désaubry L. Wang D, et al. Among authors: desaubry l. Bioorg Med Chem Lett. 2020 Nov 15;30(22):127600. doi: 10.1016/j.bmcl.2020.127600. Epub 2020 Oct 6. Bioorg Med Chem Lett. 2020. PMID: 33035678 Free PMC article. Review.
98 results