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It is not "either/or": activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood.
Prog Neurobiol. 2008 Apr;84(4):329-42. doi: 10.1016/j.pneurobio.2007.12.005. Epub 2007 Dec 27.
Prog Neurobiol. 2008.
PMID: 18242816
Free PMC article.
Review.
The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo.
Miwa JM, Stevens TR, King SL, Caldarone BJ, Ibanez-Tallon I, Xiao C, Fitzsimonds RM, Pavlides C, Lester HA, Picciotto MR, Heintz N.
Miwa JM, et al.
Neuron. 2006 Sep 7;51(5):587-600. doi: 10.1016/j.neuron.2006.07.025.
Neuron. 2006.
PMID: 16950157
Free article.
Item in Clipboard
Reduction of cocaine place preference in mice lacking the protein phosphatase 1 inhibitors DARPP 32 or Inhibitor 1.
Zachariou V, Benoit-Marand M, Allen PB, Ingrassia P, Fienberg AA, Gonon F, Greengard P, Picciotto MR.
Zachariou V, et al.
Biol Psychiatry. 2002 Apr 15;51(8):612-20. doi: 10.1016/s0006-3223(01)01318-x.
Biol Psychiatry. 2002.
PMID: 11955461
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Effects of nicotine pretreatment on dopaminergic and behavioral responses to conditioned fear stress in rats: dissociation of biochemical and behavioral effects.
George TP, Picciotto MR, Verrico CD, Roth RH.
George TP, et al.
Biol Psychiatry. 2001 Feb 1;49(3):300-6. doi: 10.1016/s0006-3223(00)00928-8.
Biol Psychiatry. 2001.
PMID: 11230881
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Nicotinic modulation of mesoprefrontal dopamine neurons: pharmacologic and neuroanatomic characterization.
George TP, Verrico CD, Picciotto MR, Roth RH.
George TP, et al.
J Pharmacol Exp Ther. 2000 Oct;295(1):58-66.
J Pharmacol Exp Ther. 2000.
PMID: 10991961
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