DA013997/DA/NIDA NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1998	1
2001	1
2002	2
2003	5
2004	4
2005	4
2006	2
2008	1
2009	4
2011	5
2012	1
2013	4
2014	6
2015	2
2016	3
2017	2
2018	1
2022	1
2024	0

1

Exploring Pharmacological Functions of Alternatively Spliced Variants of the Mu Opioid Receptor Gene, Oprm1, via Gene-Targeted Animal Models.

Kang W, Liu S, Xu J, Abrimian A, Malik AF, Chien R, Adaralegbe A, Amponsah A, Cartegni L, Pintar J, Pan YX. Kang W, et al. Int J Mol Sci. 2022 Mar 10;23(6):3010. doi: 10.3390/ijms23063010. Int J Mol Sci. 2022. PMID: 35328429 Free PMC article. Review.

2

Truncated μ-Opioid Receptors With 6 Transmembrane Domains Are Essential for Opioid Analgesia.

Lu Z, Xu J, Xu M, Rossi GC, Majumdar S, Pasternak GW, Pan YX. Lu Z, et al. Anesth Analg. 2018 Mar;126(3):1050-1057. doi: 10.1213/ANE.0000000000002538. Anesth Analg. 2018. PMID: 28991118 Free PMC article.

3

Isolation and characterization of alternatively spliced variants of the mouse sigma1 receptor gene, Sigmar1.

Pan L, Pasternak DA, Xu J, Xu M, Lu Z, Pasternak GW, Pan YX. Pan L, et al. PLoS One. 2017 Mar 28;12(3):e0174694. doi: 10.1371/journal.pone.0174694. eCollection 2017. PLoS One. 2017. PMID: 28350844 Free PMC article.

4

Alternatively spliced mu opioid receptor C termini impact the diverse actions of morphine.

Xu J, Lu Z, Narayan A, Le Rouzic VP, Xu M, Hunkele A, Brown TG, Hoefer WF, Rossi GC, Rice RC, Martínez-Rivera A, Rajadhyaksha AM, Cartegni L, Bassoni DL, Pasternak GW, Pan YX. Xu J, et al. J Clin Invest. 2017 Apr 3;127(4):1561-1573. doi: 10.1172/JCI88760. Epub 2017 Mar 20. J Clin Invest. 2017. PMID: 28319053 Free PMC article.

5

Tetrapeptide Endomorphin Analogs Require Both Full Length and Truncated Splice Variants of the Mu Opioid Receptor Gene Oprm1 for Analgesia.

Marrone GF, Lu Z, Rossi G, Narayan A, Hunkele A, Marx S, Xu J, Pintar J, Majumdar S, Pan YX, Pasternak GW. Marrone GF, et al. ACS Chem Neurosci. 2016 Dec 21;7(12):1717-1727. doi: 10.1021/acschemneuro.6b00240. Epub 2016 Oct 10. ACS Chem Neurosci. 2016. PMID: 27648914 Free PMC article.

6

Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2.

Váradi A, Marrone GF, Palmer TC, Narayan A, Szabó MR, Le Rouzic V, Grinnell SG, Subrath JJ, Warner E, Kalra S, Hunkele A, Pagirsky J, Eans SO, Medina JM, Xu J, Pan YX, Borics A, Pasternak GW, McLaughlin JP, Majumdar S. Váradi A, et al. J Med Chem. 2016 Sep 22;59(18):8381-97. doi: 10.1021/acs.jmedchem.6b00748. Epub 2016 Sep 2. J Med Chem. 2016. PMID: 27556704 Free PMC article.

7

Truncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNS.

Marrone GF, Grinnell SG, Lu Z, Rossi GC, Le Rouzic V, Xu J, Majumdar S, Pan YX, Pasternak GW. Marrone GF, et al. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3663-8. doi: 10.1073/pnas.1523894113. Epub 2016 Mar 14. Proc Natl Acad Sci U S A. 2016. PMID: 26976581 Free PMC article.

8

Mediation of opioid analgesia by a truncated 6-transmembrane GPCR.

Lu Z, Xu J, Rossi GC, Majumdar S, Pasternak GW, Pan YX. Lu Z, et al. J Clin Invest. 2015 Jul 1;125(7):2626-30. doi: 10.1172/JCI81070. Epub 2015 May 26. J Clin Invest. 2015. PMID: 26011641 Free PMC article.

9

Stabilization of morphine tolerance with long-term dosing: association with selective upregulation of mu-opioid receptor splice variant mRNAs.

Xu J, Faskowitz AJ, Rossi GC, Xu M, Lu Z, Pan YX, Pasternak GW. Xu J, et al. Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):279-84. doi: 10.1073/pnas.1419183112. Epub 2014 Dec 22. Proc Natl Acad Sci U S A. 2015. PMID: 25535370 Free PMC article.

10

Differential expressions of the alternatively spliced variant mRNAs of the µ opioid receptor gene, OPRM1, in brain regions of four inbred mouse strains.

Xu J, Lu Z, Xu M, Rossi GC, Kest B, Waxman AR, Pasternak GW, Pan YX. Xu J, et al. PLoS One. 2014 Oct 24;9(10):e111267. doi: 10.1371/journal.pone.0111267. eCollection 2014. PLoS One. 2014. PMID: 25343478 Free PMC article.

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