DK21723/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1989	2
1990	2
1991	3
1992	2
1993	1
1994	1
1995	2
1996	3
1997	3
1998	4
1999	2
2000	4
2001	3
2002	2
2003	1
2004	3
2005	2
2006	1
2007	1
2008	2
2009	1
2024	0

1

Elevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophages.

Hertz AL, Bender AT, Smith KC, Gilchrist M, Amieux PS, Aderem A, Beavo JA. Hertz AL, et al. Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21978-83. doi: 10.1073/pnas.0911684106. Epub 2009 Dec 3. Proc Natl Acad Sci U S A. 2009. PMID: 19959669 Free PMC article.

2

The structure of the GAF A domain from phosphodiesterase 6C reveals determinants of cGMP binding, a conserved binding surface, and a large cGMP-dependent conformational change.

Martinez SE, Heikaus CC, Klevit RE, Beavo JA. Martinez SE, et al. J Biol Chem. 2008 Sep 19;283(38):25913-9. doi: 10.1074/jbc.M802891200. Epub 2008 Jul 9. J Biol Chem. 2008. PMID: 18614542 Free PMC article.

3

Cyclic nucleotide analogs as probes of signaling pathways.

Poppe H, Rybalkin SD, Rehmann H, Hinds TR, Tang XB, Christensen AE, Schwede F, Genieser HG, Bos JL, Doskeland SO, Beavo JA, Butt E. Poppe H, et al. Nat Methods. 2008 Apr;5(4):277-8. doi: 10.1038/nmeth0408-277. Nat Methods. 2008. PMID: 18376388 No abstract available.

4

Rosiglitazone inhibits acyl-CoA synthetase activity and fatty acid partitioning to diacylglycerol and triacylglycerol via a peroxisome proliferator-activated receptor-gamma-independent mechanism in human arterial smooth muscle cells and macrophages.

Askari B, Kanter JE, Sherrid AM, Golej DL, Bender AT, Liu J, Hsueh WA, Beavo JA, Coleman RA, Bornfeldt KE. Askari B, et al. Diabetes. 2007 Apr;56(4):1143-52. doi: 10.2337/db06-0267. Epub 2007 Jan 26. Diabetes. 2007. PMID: 17259370 Free PMC article.

5

PDE1B2 regulates cGMP and a subset of the phenotypic characteristics acquired upon macrophage differentiation from a monocyte.

Bender AT, Beavo JA. Bender AT, et al. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):460-5. doi: 10.1073/pnas.0509972102. Epub 2006 Jan 3. Proc Natl Acad Sci U S A. 2006. PMID: 16407168 Free PMC article.

6

Selective up-regulation of PDE1B2 upon monocyte-to-macrophage differentiation.

Bender AT, Ostenson CL, Wang EH, Beavo JA. Bender AT, et al. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):497-502. doi: 10.1073/pnas.0408535102. Epub 2004 Dec 29. Proc Natl Acad Sci U S A. 2005. PMID: 15625104 Free PMC article.

7

Trypanosome cyclic nucleotide phosphodiesterase 2B binds cAMP through its GAF-A domain.

Laxman S, Rascón A, Beavo JA. Laxman S, et al. J Biol Chem. 2005 Feb 4;280(5):3771-9. doi: 10.1074/jbc.M408111200. Epub 2004 Nov 24. J Biol Chem. 2005. PMID: 15563461 Free article.

8

Differentiation of human monocytes in vitro with granulocyte-macrophage colony-stimulating factor and macrophage colony-stimulating factor produces distinct changes in cGMP phosphodiesterase expression.

Bender AT, Ostenson CL, Giordano D, Beavo JA. Bender AT, et al. Cell Signal. 2004 Mar;16(3):365-74. doi: 10.1016/j.cellsig.2003.08.009. Cell Signal. 2004. PMID: 14687666

9

Cyclic GMP phosphodiesterases and regulation of smooth muscle function.

Rybalkin SD, Yan C, Bornfeldt KE, Beavo JA. Rybalkin SD, et al. Circ Res. 2003 Aug 22;93(4):280-91. doi: 10.1161/01.RES.0000087541.15600.2B. Circ Res. 2003. PMID: 12933699 Review.

10

Cloning and characterization of a cAMP-specific phosphodiesterase (TbPDE2B) from Trypanosoma brucei.

Rascón A, Soderling SH, Schaefer JB, Beavo JA. Rascón A, et al. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4714-9. doi: 10.1073/pnas.002031599. Proc Natl Acad Sci U S A. 2002. PMID: 11930017 Free PMC article.

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