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Treatment Trials in Young Patients with Chronic Obstructive Pulmonary Disease and Pre-Chronic Obstructive Pulmonary Disease Patients: Time to Move Forward.
Martinez FJ, Agusti A, Celli BR, Han MK, Allinson JP, Bhatt SP, Calverley P, Chotirmall SH, Chowdhury B, Darken P, Da Silva CA, Donaldson G, Dorinsky P, Dransfield M, Faner R, Halpin DM, Jones P, Krishnan JA, Locantore N, Martinez FD, Mullerova H, Price D, Rabe KF, Reisner C, Singh D, Vestbo J, Vogelmeier CF, Wise RA, Tal-Singer R, Wedzicha JA. Martinez FJ, et al. Among authors: da silva ca. Am J Respir Crit Care Med. 2022 Feb 1;205(3):275-287. doi: 10.1164/rccm.202107-1663SO. Am J Respir Crit Care Med. 2022. PMID: 34672872 Free PMC article. Review.
A novel endpoint for exacerbations in asthma to accelerate clinical development: a post-hoc analysis of randomised controlled trials.
Fuhlbrigge AL, Bengtsson T, Peterson S, Jauhiainen A, Eriksson G, Da Silva CA, Johnson A, Sethi T, Locantore N, Tal-Singer R, Fagerås M. Fuhlbrigge AL, et al. Among authors: da silva ca. Lancet Respir Med. 2017 Jul;5(7):577-590. doi: 10.1016/S2213-2600(17)30218-7. Epub 2017 Jun 2. Lancet Respir Med. 2017. PMID: 28583396 Clinical Trial.
The novel bronchodilator navafenterol: a phase 2a, multicentre, randomised, double-blind, placebo-controlled crossover trial in COPD.
Singh D, Beier J, Astbury C, Belvisi MG, Da Silva CA, Jauhiainen A, Jimenez E, Lei A, Necander S, Smith JA, Wählby Hamrén U, Xin W, Psallidas I. Singh D, et al. Among authors: da silva ca. Eur Respir J. 2022 Apr 7;59(4):2100972. doi: 10.1183/13993003.00972-2021. Print 2022 Apr. Eur Respir J. 2022. PMID: 34503985 Free PMC article. Clinical Trial.
Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium.
Murray LA, Dunmore R, Camelo A, Da Silva CA, Gustavsson MJ, Habiel DM, Hackett TL, Hogaboam CM, Sleeman MA, Knight DA. Murray LA, et al. Among authors: da silva ca. Respir Res. 2017 May 3;18(1):82. doi: 10.1186/s12931-017-0565-2. Respir Res. 2017. PMID: 28468623 Free PMC article.
INEXAS: A Phase 2 Randomized Trial of On-demand Inhaled Interferon Beta-1a in Severe Asthmatics.
McCrae C, Olsson M, Gustafson P, Malmgren A, Aurell M, Fagerås M, Da Silva CA, Cavallin A, Paraskos J, Karlsson K, Wingren C, Monk P, Marsden R, Harrison T. McCrae C, et al. Among authors: da silva ca. Clin Exp Allergy. 2021 Feb;51(2):273-283. doi: 10.1111/cea.13765. Epub 2020 Nov 3. Clin Exp Allergy. 2021. PMID: 33091192 Free PMC article. Clinical Trial.
Impact of season and geography on CompEx Asthma: a composite end-point for exacerbations.
Jauhiainen A, Scheepers LEJM, Fuhlbrigge AL, Harrison T, Zangrilli J, Garcia Gil E, Gustafson P, Fagerås M, Da Silva CA. Jauhiainen A, et al. Among authors: da silva ca. ERJ Open Res. 2020 Oct 19;6(4):00246-2020. doi: 10.1183/23120541.00246-2020. eCollection 2020 Oct. ERJ Open Res. 2020. PMID: 33123561 Free PMC article.
Use of CompEx in eosinophilic patients with severe, uncontrolled asthma on benralizumab.
Bolton C, Harrison T, Lugogo N, Fuhlbrigge A, Hirsch I, Bengtsson T, Peterson S, Sidaway M, Garcia Gil E, Fagerås M, Da Silva CA. Bolton C, et al. Among authors: da silva ca. ERJ Open Res. 2024 Mar 18;10(2):01025-2023. doi: 10.1183/23120541.01025-2023. eCollection 2024 Mar. ERJ Open Res. 2024. PMID: 38500798 Free PMC article.
278 results