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The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the agonist.
Forsman H, Salomonsson E, Onnheim K, Karlsson J, Björstad A, Leffler H, Bylund J, Karlsson A, Dahlgren C. Forsman H, et al. Among authors: dahlgren c. Glycobiology. 2008 Nov;18(11):905-12. doi: 10.1093/glycob/cwn081. Epub 2008 Aug 25. Glycobiology. 2008. PMID: 18725453
The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop.
Forsman H, Bylund J, Oprea TI, Karlsson A, Boulay F, Rabiet MJ, Dahlgren C. Forsman H, et al. Among authors: dahlgren c. Biochim Biophys Acta. 2013 Aug;1833(8):1914-23. doi: 10.1016/j.bbamcr.2013.03.026. Epub 2013 Apr 2. Biochim Biophys Acta. 2013. PMID: 23562731 Free article.
334 results