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11,816 results

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Immune-evasive human islet-like organoids ameliorate diabetes.
Yoshihara E, O'Connor C, Gasser E, Wei Z, Oh TG, Tseng TW, Wang D, Cayabyab F, Dai Y, Yu RT, Liddle C, Atkins AR, Downes M, Evans RM. Yoshihara E, et al. Among authors: dai y. Nature. 2020 Oct;586(7830):606-611. doi: 10.1038/s41586-020-2631-z. Epub 2020 Aug 19. Nature. 2020. PMID: 32814902 Free PMC article.
ERRγ Preserves Brown Fat Innate Thermogenic Activity.
Ahmadian M, Liu S, Reilly SM, Hah N, Fan W, Yoshihara E, Jha P, De Magalhaes Filho CD, Jacinto S, Gomez AV, Dai Y, Yu RT, Liddle C, Atkins AR, Auwerx J, Saltiel AR, Downes M, Evans RM. Ahmadian M, et al. Among authors: dai y. Cell Rep. 2018 Mar 13;22(11):2849-2859. doi: 10.1016/j.celrep.2018.02.061. Cell Rep. 2018. PMID: 29539415 Free PMC article.
Vitamin D Switches BAF Complexes to Protect β Cells.
Wei Z, Yoshihara E, He N, Hah N, Fan W, Pinto AFM, Huddy T, Wang Y, Ross B, Estepa G, Dai Y, Ding N, Sherman MH, Fang S, Zhao X, Liddle C, Atkins AR, Yu RT, Downes M, Evans RM. Wei Z, et al. Among authors: dai y. Cell. 2018 May 17;173(5):1135-1149.e15. doi: 10.1016/j.cell.2018.04.013. Epub 2018 May 10. Cell. 2018. PMID: 29754817 Free PMC article.
FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes.
Abu-Odeh M, Zhang Y, Reilly SM, Ebadat N, Keinan O, Valentine JM, Hafezi-Bakhtiari M, Ashayer H, Mamoun L, Zhou X, Zhang J, Yu RT, Dai Y, Liddle C, Downes M, Evans RM, Kliewer SA, Mangelsdorf DJ, Saltiel AR. Abu-Odeh M, et al. Among authors: dai y. Cell Rep. 2021 Jun 29;35(13):109331. doi: 10.1016/j.celrep.2021.109331. Cell Rep. 2021. PMID: 34192547 Free PMC article.
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes.
Keinan O, Valentine JM, Xiao H, Mahata SK, Reilly SM, Abu-Odeh M, Deluca JH, Dadpey B, Cho L, Pan A, Yu RT, Dai Y, Liddle C, Downes M, Evans RM, Lusis AJ, Laakso M, Chouchani ET, Rydén M, Saltiel AR. Keinan O, et al. Among authors: dai y. Nature. 2021 Nov;599(7884):296-301. doi: 10.1038/s41586-021-04019-8. Epub 2021 Oct 27. Nature. 2021. PMID: 34707293 Free PMC article.
FGF1 and insulin control lipolysis by convergent pathways.
Sancar G, Liu S, Gasser E, Alvarez JG, Moutos C, Kim K, van Zutphen T, Wang Y, Huddy TF, Ross B, Dai Y, Zepeda D, Collins B, Tilley E, Kolar MJ, Yu RT, Atkins AR, van Dijk TH, Saghatelian A, Jonker JW, Downes M, Evans RM. Sancar G, et al. Among authors: dai y. Cell Metab. 2022 Jan 4;34(1):171-183.e6. doi: 10.1016/j.cmet.2021.12.004. Cell Metab. 2022. PMID: 34986332 Free PMC article.
Inhibiting stromal Class I HDACs curbs pancreatic cancer progression.
Liang G, Oh TG, Hah N, Tiriac H, Shi Y, Truitt ML, Antal CE, Atkins AR, Li Y, Fraser C, Ng S, Pinto AFM, Nelson DC, Estepa G, Bashi S, Banayo E, Dai Y, Liddle C, Yu RT, Hunter T, Engle DD, Han H, Von Hoff DD, Downes M, Evans RM. Liang G, et al. Among authors: dai y. Nat Commun. 2023 Dec 6;14(1):7791. doi: 10.1038/s41467-023-42178-6. Nat Commun. 2023. PMID: 38057326 Free PMC article.
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