Dailu Chen[Author] - Search Results

Year	Number of Results
2018	1
2019	1
2020	1
2021	2
2022	1
2023	5
2024	1

1

Structural basis of insulin fibrillation.

Wang L, Hall CE, Uchikawa E, Chen D, Choi E, Zhang X, Bai XC. Wang L, et al. Among authors: chen d. Sci Adv. 2023 Sep 15;9(37):eadi1057. doi: 10.1126/sciadv.adi1057. Epub 2023 Sep 15. Sci Adv. 2023. PMID: 37713485 Free PMC article.

2

FTD-tau S320F mutation stabilizes local structure and allosterically promotes amyloid motif-dependent aggregation.

Chen D, Bali S, Singh R, Wosztyl A, Mullapudi V, Vaquer-Alicea J, Jayan P, Melhem S, Seelaar H, van Swieten JC, Diamond MI, Joachimiak LA. Chen D, et al. Nat Commun. 2023 Mar 23;14(1):1625. doi: 10.1038/s41467-023-37274-6. Nat Commun. 2023. PMID: 36959205 Free PMC article.

3

Saturation mutagenesis of α-synuclein reveals monomer fold that modulates aggregation.

Chlebowicz J, Russ W, Chen D, Vega A, Vernino S, White CL 3rd, Rizo J, Joachimiak LA, Diamond MI. Chlebowicz J, et al. Among authors: chen d. Sci Adv. 2023 Oct 27;9(43):eadh3457. doi: 10.1126/sciadv.adh3457. Epub 2023 Oct 27. Sci Adv. 2023. PMID: 37889966 Free PMC article.

4

Seed-competent tau monomer initiates pathology in a tauopathy mouse model.

Mirbaha H, Chen D, Mullapudi V, Terpack SJ, White CL 3rd, Joachimiak LA, Diamond MI. Mirbaha H, et al. Among authors: chen d. J Biol Chem. 2022 Aug;298(8):102163. doi: 10.1016/j.jbc.2022.102163. Epub 2022 Jun 22. J Biol Chem. 2022. PMID: 35750209 Free PMC article.

5

Biophysical properties of a tau seed.

Hou Z, Chen D, Ryder BD, Joachimiak LA. Hou Z, et al. Among authors: chen d. Sci Rep. 2021 Jun 30;11(1):13602. doi: 10.1038/s41598-021-93093-z. Sci Rep. 2021. PMID: 34193922 Free PMC article.

6

Ensemble-based design of tau to inhibit aggregation while preserving biological activity.

Bali S, Singh R, Wydorski PM, Wosztyl A, Perez VA, Chen D, Rizo J, Joachimiak LA. Bali S, et al. Among authors: chen d. bioRxiv [Preprint]. 2023 Dec 14:2023.12.13.571598. doi: 10.1101/2023.12.13.571598. bioRxiv. 2023. PMID: 38168322 Free PMC article. Preprint.

7

Cross-Linking Mass Spectrometry Analysis of Metastable Compact Structures in Intrinsically Disordered Proteins.

Chen D, Joachimiak LA. Chen D, et al. Methods Mol Biol. 2023;2551:189-201. doi: 10.1007/978-1-0716-2597-2_13. Methods Mol Biol. 2023. PMID: 36310204

8

Inert and seed-competent tau monomers suggest structural origins of aggregation.

Mirbaha H, Chen D, Morazova OA, Ruff KM, Sharma AM, Liu X, Goodarzi M, Pappu RV, Colby DW, Mirzaei H, Joachimiak LA, Diamond MI. Mirbaha H, et al. Among authors: chen d. Elife. 2018 Jul 10;7:e36584. doi: 10.7554/eLife.36584. Elife. 2018. PMID: 29988016 Free PMC article.

9

Spontaneous motor-behavior abnormalities in two Drosophila models of neurodevelopmental disorders.

Andrew DR, Moe ME, Chen D, Tello JA, Doser RL, Conner WE, Ghuman JK, Restifo LL. Andrew DR, et al. Among authors: chen d. J Neurogenet. 2021 Mar;35(1):1-22. doi: 10.1080/01677063.2020.1833005. Epub 2020 Nov 9. J Neurogenet. 2021. PMID: 33164597

10

Tau local structure shields an amyloid-forming motif and controls aggregation propensity.

Chen D, Drombosky KW, Hou Z, Sari L, Kashmer OM, Ryder BD, Perez VA, Woodard DR, Lin MM, Diamond MI, Joachimiak LA. Chen D, et al. Nat Commun. 2019 Jun 7;10(1):2493. doi: 10.1038/s41467-019-10355-1. Nat Commun. 2019. PMID: 31175300 Free PMC article.

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