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PTPσ inhibitors promote hematopoietic stem cell regeneration.
Zhang Y, Roos M, Himburg H, Termini CM, Quarmyne M, Li M, Zhao L, Kan J, Fang T, Yan X, Pohl K, Diers E, Jin Gim H, Damoiseaux R, Whitelegge J, McBride W, Jung ME, Chute JP. Zhang Y, et al. Among authors: damoiseaux r. Nat Commun. 2019 Aug 14;10(1):3667. doi: 10.1038/s41467-019-11490-5. Nat Commun. 2019. PMID: 31413255 Free PMC article.
Nonaminoglycoside compounds induce readthrough of nonsense mutations.
Du L, Damoiseaux R, Nahas S, Gao K, Hu H, Pollard JM, Goldstine J, Jung ME, Henning SM, Bertoni C, Gatti RA. Du L, et al. Among authors: damoiseaux r. J Exp Med. 2009 Sep 28;206(10):2285-97. doi: 10.1084/jem.20081940. Epub 2009 Sep 21. J Exp Med. 2009. PMID: 19770270 Free PMC article.
High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones.
Kim K, Pollard JM, Norris AJ, McDonald JT, Sun Y, Micewicz E, Pettijohn K, Damoiseaux R, Iwamoto KS, Sayre JW, Price BD, Gatti RA, McBride WH. Kim K, et al. Among authors: damoiseaux r. Clin Cancer Res. 2009 Dec 1;15(23):7238-45. doi: 10.1158/1078-0432.CCR-09-1964. Epub 2009 Nov 17. Clin Cancer Res. 2009. PMID: 19920105 Free PMC article.
Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase.
Aghajan M, Jonai N, Flick K, Fu F, Luo M, Cai X, Ouni I, Pierce N, Tang X, Lomenick B, Damoiseaux R, Hao R, Del Moral PM, Verma R, Li Y, Li C, Houk KN, Jung ME, Zheng N, Huang L, Deshaies RJ, Kaiser P, Huang J. Aghajan M, et al. Among authors: damoiseaux r. Nat Biotechnol. 2010 Jul;28(7):738-42. doi: 10.1038/nbt.1645. Epub 2010 Jun 27. Nat Biotechnol. 2010. PMID: 20581845 Free PMC article.
Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography.
Murphy JM, Armijo AL, Nomme J, Lee CH, Smith QA, Li Z, Campbell DO, Liao HI, Nathanson DA, Austin WR, Lee JT, Darvish R, Wei L, Wang J, Su Y, Damoiseaux R, Sadeghi S, Phelps ME, Herschman HR, Czernin J, Alexandrova AN, Jung ME, Lavie A, Radu CG. Murphy JM, et al. Among authors: damoiseaux r. J Med Chem. 2013 Sep 12;56(17):6696-708. doi: 10.1021/jm400457y. Epub 2013 Aug 15. J Med Chem. 2013. PMID: 23947754 Free PMC article.
Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses.
Gillespie EJ, Ho CL, Balaji K, Clemens DL, Deng G, Wang YE, Elsaesser HJ, Tamilselvam B, Gargi A, Dixon SD, France B, Chamberlain BT, Blanke SR, Cheng G, de la Torre JC, Brooks DG, Jung ME, Colicelli J, Damoiseaux R, Bradley KA. Gillespie EJ, et al. Among authors: damoiseaux r. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):E4904-12. doi: 10.1073/pnas.1302334110. Epub 2013 Nov 4. Proc Natl Acad Sci U S A. 2013. PMID: 24191014 Free PMC article.
269 results