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Dictyostelium discoideum as a pharmacological model system to study the mechanisms of medicinal drugs and natural products.
Int J Dev Biol. 2019;63(8-9-10):541-550. doi: 10.1387/ijdb.190228rw.
Int J Dev Biol. 2019.
PMID: 31840791
Free article.
Review.
Phytocannabinoid-dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity.
Damstra-Oddy JL, Warren EC, Perry CJ, Desfougères Y, Fitzpatrick JK, Schaf J, Costelloe L, Hind W, Downer EJ, Saiardi A, Williams RSB.
Damstra-Oddy JL, et al.
Br J Pharmacol. 2021 Mar;178(5):1149-1163. doi: 10.1111/bph.15351. Epub 2021 Jan 18.
Br J Pharmacol. 2021.
PMID: 33347604
Free PMC article.
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Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling.
Warren EC, Dooves S, Lugarà E, Damstra-Oddy J, Schaf J, Heine VM, Walker MC, Williams RSB.
Warren EC, et al. Among authors: damstra oddy j.
Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23617-23625. doi: 10.1073/pnas.2008980117. Epub 2020 Sep 2.
Proc Natl Acad Sci U S A. 2020.
PMID: 32879008
Free PMC article.
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A Dictyostelium discoideum mitochondrial fluorescent tagging vector that does not affect respiratory function.
Perry CJ, Warren EC, Damstra-Oddy JL, Storey C, Francione LM, Annesley SJ, Fisher PR, Müller-Taubenberger A, Williams RSB.
Perry CJ, et al. Among authors: damstra oddy jl.
Biochem Biophys Rep. 2020 Mar 25;22:100751. doi: 10.1016/j.bbrep.2020.100751. eCollection 2020 Jul.
Biochem Biophys Rep. 2020.
PMID: 32258439
Free PMC article.
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A new mechanism for cannabidiol in regulating the one-carbon cycle and methionine levels in Dictyostelium and in mammalian epilepsy models.
Perry CJ, Finch P, Müller-Taubenberger A, Leung KY, Warren EC, Damstra-Oddy J, Sharma D, Patra PH, Glyn S, Boberska J, Stewart B, Baldwin A, Piscitelli F, Harvey RJ, Harwood A, Thompson C, Claus SP, Greene NDE, McNeish AJ, Williams CM, Whalley BJ, Williams RSB.
Perry CJ, et al. Among authors: damstra oddy j.
Br J Pharmacol. 2020 Feb;177(4):912-928. doi: 10.1111/bph.14892. Epub 2020 Jan 3.
Br J Pharmacol. 2020.
PMID: 31693171
Free PMC article.
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