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Novel meriolin derivatives as rapid apoptosis inducers.
Drießen D, Stuhldreier F, Frank A, Stark H, Wesselborg S, Stork B, Müller TJJ. Drießen D, et al. Bioorg Med Chem. 2019 Aug 1;27(15):3463-3468. doi: 10.1016/j.bmc.2019.06.029. Epub 2019 Jun 19. Bioorg Med Chem. 2019. PMID: 31248707
Nature-Inspired (di)Azine-Bridged Bisindole Alkaloids with Potent Antibacterial In Vitro and In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus.
Rehberg N, Sommer GA, Drießen D, Kruppa M, Adeniyi ET, Chen S, Wang L, Wolf K, Tasch BOA, Ioerger TR, Zhu K, Müller TJJ, Kalscheuer R. Rehberg N, et al. Among authors: driessen d. J Med Chem. 2020 Nov 12;63(21):12623-12641. doi: 10.1021/acs.jmedchem.0c00826. Epub 2020 Oct 25. J Med Chem. 2020. PMID: 33103423
Novel meriolin derivatives activate the mitochondrial apoptosis pathway in the presence of antiapoptotic Bcl-2.
Schmitt L, Lechtenberg I, Drießen D, Flores-Romero H, Skowron MA, Sekeres M, Hoppe J, Krings KS, Llewellyn TR, Peter C, Stork B, Qin N, Bhatia S, Nettersheim D, Fritz G, García-Sáez AJ, Müller TJJ, Wesselborg S. Schmitt L, et al. Among authors: driessen d. Cell Death Discov. 2024 Mar 9;10(1):125. doi: 10.1038/s41420-024-01901-y. Cell Death Discov. 2024. PMID: 38461295 Free PMC article.