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Identification of unique microRNA expression patterns in bone marrow hematopoietic stem and progenitor cells after hemorrhagic shock and multiple injuries in young and old adult mice.
Darden DB, Mira JC, Lopez MC, Stortz JA, Fenner BP, Kelly LS, Nacionales DC, Budharaju A, Loftus TJ, Baker HV, Moore FA, Brakenridge SC, Moldawer LL, Mohr AM, Efron PA. Darden DB, et al. J Trauma Acute Care Surg. 2021 Oct 1;91(4):692-699. doi: 10.1097/TA.0000000000003350. J Trauma Acute Care Surg. 2021. PMID: 34252063 Free PMC article.
Identification of Unique mRNA and miRNA Expression Patterns in Bone Marrow Hematopoietic Stem and Progenitor Cells After Trauma in Older Adults.
Darden DB, Stortz JA, Hollen MK, Cox MC, Apple CG, Hawkins RB, Rincon JC, Lopez MC, Wang Z, Navarro E, Hagen JE, Parvataneni HK, Brusko MA, Kladde M, Bacher R, Brumback BA, Brakenridge SC, Baker HV, Cogle CR, Mohr AM, Efron PA. Darden DB, et al. Front Immunol. 2020 Jun 24;11:1289. doi: 10.3389/fimmu.2020.01289. eCollection 2020. Front Immunol. 2020. PMID: 32670283 Free PMC article.
Septic Stability? Gut Microbiota in Young Adult Mice Maintains Overall Stability After Sepsis Compared to Old Adult Mice.
Mankowski RT, Thomas RM, Darden DB, Gharaibeh RZ, Hawkins RB, Cox MC, Apple C, Nacionales DC, Ungaro RF, Dirain ML, Moore FA, Leeuwenburgh C, Brakenridge SC, Clanton TL, Laitano O, Moldawer LL, Mohr AM, Efron PA. Mankowski RT, et al. Among authors: darden db. Shock. 2021 Apr 1;55(4):519-525. doi: 10.1097/SHK.0000000000001648. Shock. 2021. PMID: 32826817 Free PMC article.
Stress-related changes in the gut microbiome after trauma.
Kelly LS, Apple CG, Gharaibeh R, Pons EE, Thompson CW, Kannan KB, Darden DB, Efron PA, Thomas RM, Mohr AM. Kelly LS, et al. Among authors: darden db. J Trauma Acute Care Surg. 2021 Jul 1;91(1):192-199. doi: 10.1097/TA.0000000000003209. J Trauma Acute Care Surg. 2021. PMID: 34144563 Free PMC article.
Sex differences associate with late microbiome alterations after murine surgical sepsis.
Efron PA, Darden DB, Li EC, Munley J, Kelly L, Fenner B, Nacionales DC, Ungaro RF, Dirain ML, Rincon J, Mankowski RT, Leeuwenburgh C, Moore FA, Brakenridge SC, Foster TC, Laitano O, Casadesus G, Moldawer LL, Mohr AM, Thomas RM. Efron PA, et al. Among authors: darden db. J Trauma Acute Care Surg. 2022 Aug 1;93(2):137-146. doi: 10.1097/TA.0000000000003599. Epub 2022 Mar 24. J Trauma Acute Care Surg. 2022. PMID: 35324554 Free PMC article.
Transcriptomic responses from improved murine sepsis models can better mimic human surgical sepsis.
Efron PA, Darden DB, Wang Z, Nacionales DC, Lopez MC, Hawkins RB, Cox MC, Rincon JC, Ungaro R, Dirain ML, Ghita GL, Chen T, Billiar TR, Delano MJ, Leeuwenburgh C, Bihorac A, Brakenridge SC, Moore FA, Mohr AM, Tompkins RG, Brumback BA, Baker HV, Upchurch GR, Moldawer LL. Efron PA, et al. Among authors: darden db. FASEB J. 2021 Feb;35(2):e21156. doi: 10.1096/fj.202002150R. Epub 2020 Nov 2. FASEB J. 2021. PMID: 33140449 Free PMC article.
Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study.
Darden DB, Bacher R, Brusko MA, Knight P, Hawkins RB, Cox MC, Dirain ML, Ungaro R, Nacionales DC, Rincon JC, Gauthier ML, Kladde M, Bihorac A, Brusko TM, Moore FA, Brakenridge SC, Mohr AM, Moldawer LL, Efron PA. Darden DB, et al. Shock. 2021 May 1;55(5):587-595. doi: 10.1097/SHK.0000000000001671. Shock. 2021. PMID: 33021571 Free PMC article.
29 results