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Year Number of Results
2018 2
2021 3
2022 6
2023 3
2024 0

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13 results

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Page 1
Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy.
Frank D, Patnana PK, Vorwerk J, Mao L, Gopal LM, Jung N, Hennig T, Ruhnke L, Frenz JM, Kuppusamy M, Autry R, Wei L, Sun K, Mohammed Ahmed HM, Künstner A, Busch H, Müller H, Hutter S, Hoermann G, Liu L, Xie X, Al-Matary Y, Nimmagadda SC, Cano FC, Heuser M, Thol F, Göhring G, Steinemann D, Thomale J, Leitner T, Fischer A, Rad R, Röllig C, Altmann H, Kunadt D, Berdel WE, Hüve J, Neumann F, Klingauf J, Calderon V, Opalka B, Dührsen U, Rosenbauer F, Dugas M, Varghese J, Reinhardt HC, von Bubnoff N, Möröy T, Lenz G, Batcha AMN, Giorgi M, Selvam M, Wang E, McWeeney SK, Tyner JW, Stölzel F, Mann M, Jayavelu AK, Khandanpour C. Frank D, et al. Blood. 2023 Dec 21;142(25):2175-2191. doi: 10.1182/blood.2022015752. Blood. 2023. PMID: 37756525 Free PMC article.
GFI1B acts as a metabolic regulator in hematopoiesis and acute myeloid leukemia.
Liu L, Patnana PK, Xie X, Frank D, Nimmagadda SC, Su M, Zhang D, Koenig T, Rosenbauer F, Liebmann M, Klotz L, Xu W, Vorwerk J, Neumann F, Hüve J, Unger A, Okun JG, Opalka B, Khandanpour C. Liu L, et al. Among authors: frank d. Leukemia. 2022 Sep;36(9):2196-2207. doi: 10.1038/s41375-022-01635-9. Epub 2022 Jul 8. Leukemia. 2022. PMID: 35804097 Free PMC article.
Dose-dependent expression of GFI1 alters metabolism in the haematopoietic progenitors and MLL::AF9-induced leukaemic cells.
Patnana PK, Liu L, Frank D, Nimmagadda SC, Behrens M, Ahmed H, Xie X, Liebmann M, Wei L, Gerdemann A, Thivakaran A, Humpf HU, Klotz L, Dugas M, Varghese J, Trajkovic-Arsic M, Siveke JT, Hanenberg H, Opalka B, Dührsen U, Reinhardt HC, Guenther U, von Bubnoff N, Khandanpour C. Patnana PK, et al. Among authors: frank d. Br J Haematol. 2023 Sep;202(5):1033-1048. doi: 10.1111/bjh.18939. Epub 2023 Jul 9. Br J Haematol. 2023. PMID: 37423893
Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCs.
Xie X, Patnana PK, Frank D, Schütte J, Al-Matary Y, Künstner A, Busch H, Ahmed H, Liu L, Engel DR, Dührsen U, Rosenbauer F, Von Bubnoff N, Lenz G, Khandanpour C. Xie X, et al. Among authors: frank d. Front Cell Dev Biol. 2023 Apr 5;11:866847. doi: 10.3389/fcell.2023.866847. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37091981 Free PMC article.
Dexamethasone-mediated inhibition of Notch signalling blocks the interaction of leukaemia and mesenchymal stromal cells.
Ahmed HMM, Nimmagadda SC, Al-Matary YS, Fiori M, May T, Frank D, Patnana PK, Récher C, Schliemann C, Mikesch JH, Koenig T, Rosenbauer F, Hartmann W, Tuckermann J, Dührsen U, Lanying W, Dugas M, Opalka B, Lenz G, Khandanpour C. Ahmed HMM, et al. Among authors: frank d. Br J Haematol. 2022 Feb;196(4):995-1006. doi: 10.1111/bjh.17940. Epub 2021 Nov 18. Br J Haematol. 2022. PMID: 34792186
Inhibiting PI3K-AKT-mTOR Signaling in Multiple Myeloma-Associated Mesenchymal Stem Cells Impedes the Proliferation of Multiple Myeloma Cells.
Heinemann L, Möllers KM, Ahmed HMM, Wei L, Sun K, Nimmagadda SC, Frank D, Baumann A, Poos AM, Dugas M, Varghese J, Raab MS, Khandanpour C. Heinemann L, et al. Among authors: frank d. Front Oncol. 2022 Jun 20;12:874325. doi: 10.3389/fonc.2022.874325. eCollection 2022. Front Oncol. 2022. PMID: 35795041 Free PMC article.
13 results