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Lysine Deacetylases and Regulated Glycolysis in Macrophages.
Shakespear MR, Iyer A, Cheng CY, Das Gupta K, Singhal A, Fairlie DP, Sweet MJ. Shakespear MR, et al. Among authors: das gupta k. Trends Immunol. 2018 Jun;39(6):473-488. doi: 10.1016/j.it.2018.02.009. Epub 2018 Mar 19. Trends Immunol. 2018. PMID: 29567326 Review.
Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2.
Das Gupta K, Shakespear MR, Curson JEB, Murthy AMV, Iyer A, Hodson MP, Ramnath D, Tillu VA, von Pein JB, Reid RC, Tunny K, Hohenhaus DM, Moradi SV, Kelly GM, Kobayashi T, Gunter JH, Stevenson AJ, Xu W, Luo L, Jones A, Johnston WA, Blumenthal A, Alexandrov K, Collins BM, Stow JL, Fairlie DP, Sweet MJ. Das Gupta K, et al. Cell Rep. 2020 Feb 25;30(8):2712-2728.e8. doi: 10.1016/j.celrep.2020.02.007. Cell Rep. 2020. PMID: 32101747 Free article.
Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells.
Sun X, Cao B, Naval-Sanchez M, Pham T, Sun YBY, Williams B, Heazlewood SY, Deshpande N, Li J, Kraus F, Rae J, Nguyen Q, Yari H, Schröder J, Heazlewood CK, Fulton M, Hatwell-Humble J, Das Gupta K, Kapetanovic R, Chen X, Sweet MJ, Parton RG, Ryan MT, Polo JM, Nefzger CM, Nilsson SK. Sun X, et al. Among authors: das gupta k. Nat Commun. 2021 May 11;12(1):2665. doi: 10.1038/s41467-021-22863-0. Nat Commun. 2021. PMID: 33976125 Free PMC article.
HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages.
Das Gupta K, Ramnath D, von Pein JB, Curson JEB, Wang Y, Abrol R, Kakkanat A, Moradi SV, Gunther KS, Murthy AMV, Stocks CJ, Kapetanovic R, Reid RC, Iyer A, Ilka ZC, Nauseef WM, Plan M, Luo L, Stow JL, Schroder K, Karunakaran D, Alexandrov K, Shakespear MR, Schembri MA, Fairlie DP, Sweet MJ. Das Gupta K, et al. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2212813120. doi: 10.1073/pnas.2212813120. Epub 2023 Jan 17. Proc Natl Acad Sci U S A. 2023. PMID: 36649417 Free PMC article.
42 results