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Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones.
Maes C, Goossens S, Bartunkova S, Drogat B, Coenegrachts L, Stockmans I, Moermans K, Nyabi O, Haigh K, Naessens M, Haenebalcke L, Tuckermann JP, Tjwa M, Carmeliet P, Mandic V, David JP, Behrens A, Nagy A, Carmeliet G, Haigh JJ. Maes C, et al. Among authors: david jp. EMBO J. 2010 Jan 20;29(2):424-41. doi: 10.1038/emboj.2009.361. Epub 2009 Dec 10. EMBO J. 2010. PMID: 20010698 Free PMC article.
Essential role of RSK2 in c-Fos-dependent osteosarcoma development.
David JP, Mehic D, Bakiri L, Schilling AF, Mandic V, Priemel M, Idarraga MH, Reschke MO, Hoffmann O, Amling M, Wagner EF. David JP, et al. J Clin Invest. 2005 Mar;115(3):664-72. doi: 10.1172/JCI22877. J Clin Invest. 2005. PMID: 15719069 Free PMC article.
Elevated Fra-1 expression causes severe lipodystrophy.
Luther J, Driessler F, Megges M, Hess A, Herbort B, Mandic V, Zaiss MM, Reichardt A, Zech C, Tuckermann JP, Calkhoven CF, Wagner EF, Schett G, David JP. Luther J, et al. Among authors: david jp. J Cell Sci. 2011 May 1;124(Pt 9):1465-76. doi: 10.1242/jcs.079855. Epub 2011 Apr 12. J Cell Sci. 2011. PMID: 21486951
RSK2 protects mice against TNF-induced bone loss.
Böhm C, Derer A, Axmann R, Hillienhoff U, Zaiss MM, Luther J, Zech C, Stock M, Scholtysek C, Engelke K, Hess A, Tuckermann JP, Schett G, David JP. Böhm C, et al. Among authors: david jp. J Cell Sci. 2012 May 1;125(Pt 9):2160-71. doi: 10.1242/jcs.096008. Epub 2012 Feb 17. J Cell Sci. 2012. PMID: 22344264
Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.
Rauch A, Seitz S, Baschant U, Schilling AF, Illing A, Stride B, Kirilov M, Mandic V, Takacz A, Schmidt-Ullrich R, Ostermay S, Schinke T, Spanbroek R, Zaiss MM, Angel PE, Lerner UH, David JP, Reichardt HM, Amling M, Schütz G, Tuckermann JP. Rauch A, et al. Among authors: david jp. Cell Metab. 2010 Jun 9;11(6):517-31. doi: 10.1016/j.cmet.2010.05.005. Cell Metab. 2010. PMID: 20519123 Free article.
283 results