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Identification of genomic enhancers through spatial integration of single-cell transcriptomics and epigenomics.
Bravo González-Blas C, Quan XJ, Duran-Romaña R, Taskiran II, Koldere D, Davie K, Christiaens V, Makhzami S, Hulselmans G, de Waegeneer M, Mauduit D, Poovathingal S, Aibar S, Aerts S. Bravo González-Blas C, et al. Among authors: davie k. Mol Syst Biol. 2020 May;16(5):e9438. doi: 10.15252/msb.20209438. Mol Syst Biol. 2020. PMID: 32431014 Free PMC article.
Multiplex enhancer-reporter assays uncover unsophisticated TP53 enhancer logic.
Verfaillie A, Svetlichnyy D, Imrichova H, Davie K, Fiers M, Kalender Atak Z, Hulselmans G, Christiaens V, Aerts S. Verfaillie A, et al. Among authors: davie k. Genome Res. 2016 Jul;26(7):882-95. doi: 10.1101/gr.204149.116. Epub 2016 May 18. Genome Res. 2016. PMID: 27197205 Free PMC article.
The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes.
Jacobs J, Atkins M, Davie K, Imrichova H, Romanelli L, Christiaens V, Hulselmans G, Potier D, Wouters J, Taskiran II, Paciello G, González-Blas CB, Koldere D, Aibar S, Halder G, Aerts S. Jacobs J, et al. Among authors: davie k. Nat Genet. 2018 Jul;50(7):1011-1020. doi: 10.1038/s41588-018-0140-x. Epub 2018 Jun 4. Nat Genet. 2018. PMID: 29867222 Free PMC article.
A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain.
Davie K, Janssens J, Koldere D, De Waegeneer M, Pech U, Kreft Ł, Aibar S, Makhzami S, Christiaens V, Bravo González-Blas C, Poovathingal S, Hulselmans G, Spanier KI, Moerman T, Vanspauwen B, Geurs S, Voet T, Lammertyn J, Thienpont B, Liu S, Konstantinides N, Fiers M, Verstreken P, Aerts S. Davie K, et al. Cell. 2018 Aug 9;174(4):982-998.e20. doi: 10.1016/j.cell.2018.05.057. Epub 2018 Jun 18. Cell. 2018. PMID: 29909982 Free PMC article.
cisTopic: cis-regulatory topic modeling on single-cell ATAC-seq data.
Bravo González-Blas C, Minnoye L, Papasokrati D, Aibar S, Hulselmans G, Christiaens V, Davie K, Wouters J, Aerts S. Bravo González-Blas C, et al. Among authors: davie k. Nat Methods. 2019 May;16(5):397-400. doi: 10.1038/s41592-019-0367-1. Epub 2019 Apr 8. Nat Methods. 2019. PMID: 30962623 Free PMC article.
Xenotransplanted Human Cortical Neurons Reveal Species-Specific Development and Functional Integration into Mouse Visual Circuits.
Linaro D, Vermaercke B, Iwata R, Ramaswamy A, Libé-Philippot B, Boubakar L, Davis BA, Wierda K, Davie K, Poovathingal S, Penttila PA, Bilheu A, De Bruyne L, Gall D, Conzelmann KK, Bonin V, Vanderhaeghen P. Linaro D, et al. Among authors: davie k. Neuron. 2019 Dec 4;104(5):972-986.e6. doi: 10.1016/j.neuron.2019.10.002. Epub 2019 Nov 21. Neuron. 2019. PMID: 31761708 Free PMC article.
Genomic adaptations to aquatic and aerial life in mayflies and the origin of insect wings.
Almudi I, Vizueta J, Wyatt CDR, de Mendoza A, Marlétaz F, Firbas PN, Feuda R, Masiero G, Medina P, Alcaina-Caro A, Cruz F, Gómez-Garrido J, Gut M, Alioto TS, Vargas-Chavez C, Davie K, Misof B, González J, Aerts S, Lister R, Paps J, Rozas J, Sánchez-Gracia A, Irimia M, Maeso I, Casares F. Almudi I, et al. Among authors: davie k. Nat Commun. 2020 May 26;11(1):2631. doi: 10.1038/s41467-020-16284-8. Nat Commun. 2020. PMID: 32457347 Free PMC article.
25 results