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Downregulation of Keap1 Confers Features of a Fasted Metabolic State.
Knatko EV, Tatham MH, Zhang Y, Castro C, Higgins M, Dayalan Naidu S, Leonardi C, de la Vega L, Honda T, Griffin JL, Hay RT, Dinkova-Kostova AT. Knatko EV, et al. Among authors: dayalan naidu s. iScience. 2020 Oct 6;23(10):101638. doi: 10.1016/j.isci.2020.101638. eCollection 2020 Oct 23. iScience. 2020. PMID: 33103077 Free PMC article.
Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation.
Zhang Y, Dayalan Naidu S, Samarasinghe K, Van Hecke GC, Pheely A, Boronina TN, Cole RN, Benjamin IJ, Cole PA, Ahn YH, Dinkova-Kostova AT. Zhang Y, et al. Among authors: dayalan naidu s. Br J Cancer. 2014 Jan 7;110(1):71-82. doi: 10.1038/bjc.2013.710. Epub 2013 Dec 5. Br J Cancer. 2014. PMID: 24322890 Free PMC article.
Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases.
Dayalan Naidu S, Sutherland C, Zhang Y, Risco A, de la Vega L, Caunt CJ, Hastie CJ, Lamont DJ, Torrente L, Chowdhry S, Benjamin IJ, Keyse SM, Cuenda A, Dinkova-Kostova AT. Dayalan Naidu S, et al. Mol Cell Biol. 2016 Aug 26;36(18):2403-17. doi: 10.1128/MCB.00292-16. Print 2016 Sep 15. Mol Cell Biol. 2016. PMID: 27354066 Free PMC article.
Regulation of the mammalian heat shock factor 1.
Dayalan Naidu S, Dinkova-Kostova AT. Dayalan Naidu S, et al. FEBS J. 2017 Jun;284(11):1606-1627. doi: 10.1111/febs.13999. Epub 2017 Feb 1. FEBS J. 2017. PMID: 28052564 Free article. Review.
KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients.
Quinti L, Dayalan Naidu S, Träger U, Chen X, Kegel-Gleason K, Llères D, Connolly C, Chopra V, Low C, Moniot S, Sapp E, Tousley AR, Vodicka P, Van Kanegan MJ, Kaltenbach LS, Crawford LA, Fuszard M, Higgins M, Miller JRC, Farmer RE, Potluri V, Samajdar S, Meisel L, Zhang N, Snyder A, Stein R, Hersch SM, Ellerby LM, Weerapana E, Schwarzschild MA, Steegborn C, Leavitt BR, Degterev A, Tabrizi SJ, Lo DC, DiFiglia M, Thompson LM, Dinkova-Kostova AT, Kazantsev AG. Quinti L, et al. Among authors: dayalan naidu s. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4676-E4685. doi: 10.1073/pnas.1614943114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533375 Free PMC article.
Transcription factors NRF2 and HSF1 have opposing functions in autophagy.
Dayalan Naidu S, Dikovskaya D, Gaurilcikaite E, Knatko EV, Healy ZR, Mohan H, Koh G, Laurell A, Ball G, Olagnier D, de la Vega L, Ganley IG, Talalay P, Dinkova-Kostova AT. Dayalan Naidu S, et al. Sci Rep. 2017 Sep 8;7(1):11023. doi: 10.1038/s41598-017-11262-5. Sci Rep. 2017. PMID: 28887499 Free PMC article.
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